ArticlePLoS neglected tropical diseases2015
Mycetoma in the Sudan: an update from the Mycetoma Research Centre, University of Khartoum, Sudan.
Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 4 of them syntheses that pooled it.
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Who cites it
87 citing papers in PubMed, 4 syntheses or guidelines pooled it, 175 citations in OpenAlex.
- Global sociodemographic, clinical, and epidemiological profiling of patients with mycetoma: A systematic review.PLoS neglected tropical diseases · 2025Pooled it
- Eumycetoma causative agents: A systematic review to inform the World Health Organization priority list of fungal pathogens.Medical mycology · 2024Pooled it
- Host genetic susceptibility to mycetoma.PLoS neglected tropical diseases · 2020Pooled it
- Mycetoma (Madura Foot) in Israel: Recent Cases and a Systematic Review of the Literature.The American journal of tropical medicine and hygiene · 2017Pooled it
- Pharmacokinetics and Pharmacodynamics of Fosravuconazole, Itraconazole, and Hydroxyitraconazole in Sudanese Patients With Eumycetoma.The Journal of infectious diseases · 2025Trial
- Mycetoma.PLoS neglected tropical diseases · 2026Review
- The Burden of Lower Limb Deformities in Low- and Lower-Middle-Income Countries: A Scoping Review.Journal of the Pediatric Orthopaedic Society of North America · 2026Review
- Left Gluteal and Perianal Eumycetoma Lesion Extending Into the Left Greater Sciatic Foramen, Pelvic Cavity to the External Anal Sphincter.Clinical case reports · 2026Article
- A critical anthropological evaluation of digital media based interventions for mycetoma in Sudan; the case of "Hope for a Devastating Neglected Disease" documentary film.International journal for equity in health · 2026Article
- Environmental and structural risk factors for mycetoma in the White Nile State, Sudan: an ethnographic study.International journal for equity in health · 2026Article
- Diagnosis and Management of a Long-Standing Eumycetoma of the Wrist in Somalia: A Case Report in a Resource-Limited Setting.International medical case reports journal · 2026Article
- Surgical Management and Antifungal Therapy for Extensive Eumycetoma of the Right Foot: A Case Report from Resource Limited Settings.International medical case reports journal · 2026Article
- Clinical presentation, etiology, and treatment outcomes of mycetoma: A 25-year retrospective study in Southern Thailand.PLoS neglected tropical diseases · 2026Article
- Advanced Eumycetoma of the Right Foot Resulting in Below-Knee Amputation in Somalia: A Case Report.International medical case reports journal · 2026Article
- Traditional healing and mycetoma management in East Sennar State (Sudan): a qualitative exploration.International journal for equity in health · 2025Article
- Superficial Fungal Infections in Children-What Do We Know?Journal of clinical medicine · 2025Review
- Medical and health students' insights into mycetoma: A survey-based study on knowledge and clinical practices.PLoS neglected tropical diseases · 2025Article
- Article
- Eumycetoma: pathogenesis, current treatments, and the search for new drugs.Applied microbiology and biotechnology · 2025Review
- Identification of Microbial-Based Natural Products as Potential CYP51 Inhibitors for Eumycetoma Treatment: Insights from Molecular Docking, MM-GBSA Calculations, ADMET Analysis, and Molecular Dynamics Simulations.Pharmaceuticals (Basel, Switzerland) · 2025Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This communication reports on the Mycetoma Research Centre of the University of Khartoum, Sudan experience on 6,792 patients seen during the period 1991-2014.The patients were predominately young (64% under 30 years old) males (76%). The majority (68%) were from the Sudan mycetoma belt and 28% were students. Madurella mycetomatis eumycetoma was the most common type (70%). In 66% of the patients the duration of the disease was less than five years, and 81% gave a history of sinuses discharging mostly black grains (78%). History of trauma at the mycetoma site was reported in 20%. Local pain was reported in 27% of the patients, and only 12% had a family history of mycetoma. The study showed that 57% of the patients had previous surgical excisions and recurrence, and only 4% received previous medical treatment for mycetoma. Other concomitant medical diseases were reported in 4% of the patients. The foot (76%) and hand (8%) were the most commonly affected sites. Less frequently affected sites were the leg and knee (7%), thigh (2%), buttock (2%) and arm and forearm (1%). Rare sites included the chest wall, head and neck, back, abdominal wall, perineum, oral cavity, tongue and eye. Multiple sites mycetoma was recorded in 135 (2%) of cases. At presentation, 37% of patients had massive lesions, 79% had sinuses, 8% had local hyper-hydrosis at the mycetoma lesion, 11% had regional lymphadenopathy, while 6% had dilated tortuous veins proximal to the mycetoma lesions. The diagnosis of mycetoma was established by combined imaging techniques and cytological, histopathological, serological tests and grain culture. Patients with actinomycetoma received a combination of antimicrobial agents, while eumycetoma patients received antifungal agents combined with various surgical excisions. Surgical excisions in the form of wide local excision, debridement or amputation were done in 807 patients, and of them 248 patients (30.7%) had postoperative recurrence. Different types of amputations were done in 120 patients (1.7%).
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