Evidence map›Paper›PMID 25815732›Full record

ArticlePloS one2015

Age and gender adjusted comparison of clinical features between severe cases infected with H7N9 and H1N1pdm influenza A in Jiangsu Province, China.

Xiang Huo, Ke Xu, Qigang Dai, Xian Qi, Huiyan Yu, Changjun Bao

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiang HuoDepartment of Acute Infectious Disease, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China, 210009.
Ke XuDepartment of Acute Infectious Disease, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China, 210009.
Qigang DaiDepartment of Acute Infectious Disease, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China, 210009.
Xian QiDepartment of Acute Infectious Disease, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China, 210009.
Huiyan YuDepartment of Acute Infectious Disease, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China, 210009.
Changjun BaoDepartment of Acute Infectious Disease, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China, 210009.
Jiangsu Provincial Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfluenza H7N9 and H1N1pdm can cause severe human infections. It is important to investigate the distinguishing clinical features between these two diseases. Several studies have compared the differences in general, however, age and gender adjusted comparisons may be more useful and informative to the health professionals.

methodsA total of 184 severe H1N1pdm patients and 37 severe H7N9 patients from Jiangsu Province were included in this analysis to perform age and gender adjusted comparison of clinical features.

resultsAfter adjusting age and gender, no significant differences in chronic medical conditions or treatment were found between severely ill patients with H7N9 and H1N1pdm. Severely ill patients with H7N9 had significantly longer interval from onset of illness to neuraminidase inhibitor treatment and to death. They were more likely to have complications such as acute respiratory distress syndrome (ARDS), liver and renal dysfunctions, and had a significantly higher risk of death.

conclusionOur results suggests that age and gender should be adjusted as important confounding factors when comparing the clinical features between severe H7N9 and H1N1pdm patients to avoid any misunderstanding regarding the differences between these two diseases particularly in terms of clinical severity and prognosis.

Indexed as

AdolescentAdultAgedAge FactorsChildChinaFemaleHumansInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H7N9 SubtypeInfluenza, HumanMaleMiddle AgedPandemicsPrognosisSex Factors

Identifiers

PMID25815732
PMCPMC4376887
OpenAlexW2083889128

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.