Evidence map›Paper›PMID 25815333›Full record

ReviewBioMed research international2015

Plant antimicrobial peptides as potential anticancer agents.

Jaquelina Julia Guzmán-Rodríguez, Alejandra Ochoa-Zarzosa, Rodolfo López-Gómez, Joel E López-Meza

Abstract readReview
In one paragraph

Review in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Review
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  7. Isolation and characterization ofFrontiers in microbiology · 2025
    Article
  8. Review
  9. Antioxidants (Basel, Switzerland) · 2024
    Article
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  12. Article
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  19. Article
  20. PaDef (Frontiers in molecular biosciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jaquelina Julia Guzmán-RodríguezCentro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás de Hidalgo, Km 9.5 Carretera Morelia-Zinapécuaro, Posta Veterinaria, 58893 Morelia, MICH, Mexico.
Alejandra Ochoa-ZarzosaCentro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás de Hidalgo, Km 9.5 Carretera Morelia-Zinapécuaro, Posta Veterinaria, 58893 Morelia, MICH, Mexico.ORCID 0000-0003-3441-2989
Rodolfo López-GómezInstituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Edif. B1, Ciudad Universitaria, 58030 Morelia, MICH, Mexico.
Joel E López-MezaCentro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás de Hidalgo, Km 9.5 Carretera Morelia-Zinapécuaro, Posta Veterinaria, 58893 Morelia, MICH, Mexico.ORCID 0000-0002-3269-9202

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial peptides (AMPs) are part of the innate immune defense mechanism of many organisms and are promising candidates to treat infections caused by pathogenic bacteria to animals and humans. AMPs also display anticancer activities because of their ability to inactivate a wide range of cancer cells. Cancer remains a cause of high morbidity and mortality worldwide. Therefore, the development of methods for its control is desirable. Attractive alternatives include plant AMP thionins, defensins, and cyclotides, which have anticancer activities. Here, we provide an overview of plant AMPs anticancer activities, with an emphasis on their mode of action, their selectivity, and their efficacy.

Indexed as

AnimalsAnti-Infective AgentsAntimicrobial Cationic PeptidesAntineoplastic AgentsCyclotidesDefensinsHumansImmunity, InnateNeoplasmsPlantsThioninsAnti-Infective AgentsAntimicrobial Cationic PeptidesAntineoplastic AgentsCyclotidesDefensinsThionins

Identifiers

PMID25815333
PMCPMC4359852

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.