Evidence map›Paper›PMID 25815164›Full record

ArticleBMC biophysics2015

Life at the mesoscale: the self-organised cytoplasm and nucleoplasm.

Richard P Sear, Ignacio Pagonabarraga, Andrew Flaus

Abstract read
In one paragraph

Article in BMC biophysics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Increased mesoscale diffusivity in response to acute glucose starvation.bioRxiv : the preprint server for biology · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Richard P SearDepartment of Physics, University of Surrey, GU2 7XH Guildford, Surrey UK.
Ignacio PagonabarragaDepartament de Fisica Fonamental, University of Barcelona, 08028 Barcelona, Spain.
Andrew FlausCentre for Chromosome Biology, School of Life Sciences, National University of Ireland Galway, Galway, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cell contains highly dynamic structures exploiting physical principles of self-organisation at the mesoscale (100 nm to 10 μm). Examples include non-membrane bound cytoplasmic bodies, cytoskeleton-based motor networks and multi-scale chromatin organisation. The challenges of mesoscale self-organisation were discussed at a CECAM workshop in July 2014. Biologists need approaches to observe highly dynamic, low affinity, low specificity associations and to perturb single structures, while biological physicists and biomathematicians need to work closely with biologists to build and validate quantitative models. A table of terminology is included to facilitate multidisciplinary efforts to reveal the richness and diversity of mesoscale cell biology.

Indexed as

Cell biologyChromatinCytoplasmic bodiesCytoskeletonMesoscaleSelf-organisationWorkshop report

Identifiers

PMID25815164
PMCPMC4374369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.