Evidence map›Paper›PMID 25815131›Full record

ReviewWorld journal of stem cells2015

Adult stem cells in neural repair: Current options, limitations and perspectives.

Eric Domingos Mariano, Manoel Jacobsen Teixeira, Suely Kazue Nagahashi Marie, Guilherme Lepski

Open access · bronzeAbstract readReview
In one paragraph

Review in World journal of stem cells, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Eric Domingos MarianoEric Domingos Mariano, Suely Kazue Nagahashi Marie, Guilherme Lepski, Department of Neurology, Medicine School, University of São Paulo, São Paulo SP 01246-903, Brazil.
Manoel Jacobsen TeixeiraEric Domingos Mariano, Suely Kazue Nagahashi Marie, Guilherme Lepski, Department of Neurology, Medicine School, University of São Paulo, São Paulo SP 01246-903, Brazil.
Suely Kazue Nagahashi MarieEric Domingos Mariano, Suely Kazue Nagahashi Marie, Guilherme Lepski, Department of Neurology, Medicine School, University of São Paulo, São Paulo SP 01246-903, Brazil.
Guilherme LepskiEric Domingos Mariano, Suely Kazue Nagahashi Marie, Guilherme Lepski, Department of Neurology, Medicine School, University of São Paulo, São Paulo SP 01246-903, Brazil.
Hospital São Domingos · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cells represent a promising step for the future of regenerative medicine. As they are able to differentiate into any cell type, tissue or organ, these cells are great candidates for treatments against the worst diseases that defy doctors and researchers around the world. Stem cells can be divided into three main groups: (1) embryonic stem cells; (2) fetal stem cells; and (3) adult stem cells. In terms of their capacity for proliferation, stem cells are also classified as totipotent, pluripotent or multipotent. Adult stem cells, also known as somatic cells, are found in various regions of the adult organism, such as bone marrow, skin, eyes, viscera and brain. They can differentiate into unipotent cells of the residing tissue, generally for the purpose of repair. These cells represent an excellent choice in regenerative medicine, every patient can be a donor of adult stem cells to provide a more customized and efficient therapy against various diseases, in other words, they allow the opportunity of autologous transplantation. But in order to start clinical trials and achieve great results, we need to understand how these cells interact with the host tissue, how they can manipulate or be manipulated by the microenvironment where they will be transplanted and for how long they can maintain their multipotent state to provide a full regeneration.

Indexed as

Adult stem cellsBone marrow stem cellsMesenchymal stem cellsNeural stem cellsOlfactory ensheathing cellsStem cellsStem cell therapy

Identifiers

PMID25815131
PMCPMC4369503
OpenAlexW1990183318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.