ReviewWorld journal of stem cells2015
Vital roles of stem cells and biomaterials in skin tissue engineering.
Review in World journal of stem cells, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 60 citations in OpenAlex.
- Research progress on scar-free healing.Annals of medicine · 2025Review
- Coordinated Development of Immune Cell Populations in Vascularized Skin Organoids from Human Induced Pluripotent Stem Cells.Advanced healthcare materials · 2025Article
- Wound Healing: Molecular Mechanisms, Antimicrobial Peptides, and Emerging Technologies in Regenerative Medicine.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Particulate 3D Hydrogels of Silk Fibroin-Pluronic to Deliver Curcumin for Infection-Free Wound Healing.Biomimetics (Basel, Switzerland) · 2024Article
- The properties of absorbable scaffold harvested with human amniotic fluid stem cells on rat model: an innovation for pelvic reconstruction surgery.Scientific reports · 2024Article
- Development of collagenous scaffolds for wound healing: characterization and in vivo analysis.Journal of materials science. Materials in medicine · 2024Article
- Advanced function, design and application of skin substitutes for skin regeneration.Materials today. Bio · 2024Review
- Current Biomaterials for Wound Healing.Bioengineering (Basel, Switzerland) · 2023Review
- From Grafts to Human Bioengineered Vascularized Skin Substitutes.International journal of molecular sciences · 2020Review
- Tissue engineering in female pelvic floor reconstruction.Engineering in life sciences · 2020Review
- Functional Skin Grafts: Where Biomaterials Meet Stem Cells.Stem cells international · 2019Review
- VEGF heparinized-decellularized adipose tissue scaffolds enhance tissue engineering vascularizationRSC advances · 2018Article
- 3D Bioprinted BioMask for Facial Skin Reconstruction.Bioprinting (Amsterdam, Netherlands) · 2018Article
- A Novel Secretory Vesicle from Deer Antlerogenic Mesenchymal Stem Cell-Conditioned Media (DaMSC-CM) Promotes Tissue Regeneration.Stem cells international · 2018Article
- Advances in keratinocyte delivery in burn wound care.Advanced drug delivery reviews · 2018Review
- Skin Tissue Engineering: Application of Adipose-Derived Stem Cells.BioMed research international · 2017Review
- Article
- Cellularized Bilayer Pullulan-Gelatin Hydrogel for Skin Regeneration.Tissue engineering. Part A · 2016Article
- Production of Highly Aligned Collagen Scaffolds by Freeze-drying of Self-assembled, Fibrillar Collagen Gels.ACS biomaterials science & engineering · 2016Article
- Characterization of A Three-Dimensional Organotypic Co-Culture Skin Model for Epidermal Differentiation of Rat Adipose-Derived Stem Cells.Cell journal · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tissue engineering essentially refers to technology for growing new human tissue and is distinct from regenerative medicine. Currently, pieces of skin are already being fabricated for clinical use and many other tissue types may be fabricated in the future. Tissue engineering was first defined in 1987 by the United States National Science Foundation which critically discussed the future targets of bioengineering research and its consequences. The principles of tissue engineering are to initiate cell cultures in vitro, grow them on scaffolds in situ and transplant the composite into a recipient in vivo. From the beginning, scaffolds have been necessary in tissue engineering applications. Regardless, the latest technology has redirected established approaches by omitting scaffolds. Currently, scientists from diverse research institutes are engineering skin without scaffolds. Due to their advantageous properties, stem cells have robustly transformed the tissue engineering field as part of an engineered bilayered skin substitute that will later be discussed in detail. Additionally, utilizing biomaterials or skin replacement products in skin tissue engineering as strategy to successfully direct cell proliferation and differentiation as well as to optimize the safety of handling during grafting is beneficial. This approach has also led to the cells' application in developing the novel skin substitute that will be briefly explained in this review.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.