Evidence map›Paper›PMID 25815123›Full record

ReviewWorld journal of stem cells2015

Tooth-derived stem cells: Update and perspectives.

Miki Taketomi Saito, Karina Gonzales Silvério, Márcio Zaffalon Casati, Enilson Antonio Sallum, Francisco Humberto Nociti

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of stem cells, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 112 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. The role of OCT4 and CD44 in lower lip carcinogenesis.Oral and maxillofacial surgery · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Research progress of biomimetic materials in oral medicine.Journal of biological engineering · 2023
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. PDGF-BB signalingFrontiers in cell and developmental biology · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Miki Taketomi SaitoMiki Taketomi Saito, Karina Gonzales Silvério, Márcio Zaffalon Casati, Enilson Antonio Sallum, Francisco Humberto Nociti Jr, Department of Prosthodontics and Periodontics, Division of Periodontics, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo 13414-903, Brazil.
Karina Gonzales SilvérioMiki Taketomi Saito, Karina Gonzales Silvério, Márcio Zaffalon Casati, Enilson Antonio Sallum, Francisco Humberto Nociti Jr, Department of Prosthodontics and Periodontics, Division of Periodontics, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo 13414-903, Brazil.
Márcio Zaffalon CasatiMiki Taketomi Saito, Karina Gonzales Silvério, Márcio Zaffalon Casati, Enilson Antonio Sallum, Francisco Humberto Nociti Jr, Department of Prosthodontics and Periodontics, Division of Periodontics, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo 13414-903, Brazil.
Enilson Antonio SallumMiki Taketomi Saito, Karina Gonzales Silvério, Márcio Zaffalon Casati, Enilson Antonio Sallum, Francisco Humberto Nociti Jr, Department of Prosthodontics and Periodontics, Division of Periodontics, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo 13414-903, Brazil.
Francisco Humberto NocitiMiki Taketomi Saito, Karina Gonzales Silvério, Márcio Zaffalon Casati, Enilson Antonio Sallum, Francisco Humberto Nociti Jr, Department of Prosthodontics and Periodontics, Division of Periodontics, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, São Paulo 13414-903, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue engineering is an emerging field of science that focuses on creating suitable conditions for the regeneration of tissues. The basic components for tissue engineering involve an interactive triad of scaffolds, signaling molecules, and cells. In this context, stem cells (SCs) present the characteristics of self-renewal and differentiation capacity, which make them promising candidates for tissue engineering. Although they present some common markers, such as cluster of differentiation (CD)105, CD146 and STRO-1, SCs derived from various tissues have different patterns in relation to proliferation, clonogenicity, and differentiation abilities in vitro and in vivo. Tooth-derived tissues have been proposed as an accessible source to obtain SCs with limited morbidity, and various tooth-derived SCs (TDSCs) have been isolated and characterized, such as dental pulp SCs, SCs from human exfoliated deciduous teeth, periodontal ligament SCs, dental follicle progenitor cells, SCs from apical papilla, and periodontal ligament of deciduous teeth SCs. However, heterogeneity among these populations has been observed, and the best method to select the most appropriate TDSCs for regeneration approaches has not yet been established. The objective of this review is to outline the current knowledge concerning the various types of TDSCs, and discuss the perspectives for their use in regenerative approaches.

Indexed as

Cell-based therapyDental stem cellsDifferentiationMesenchymal stem cellsTissue engineering

Identifiers

PMID25815123
PMCPMC4369495
OpenAlexW2016900858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.