ReviewWorld journal of stem cells2015
Stem cell therapy in inflammatory bowel disease: A promising therapeutic strategy?
Review in World journal of stem cells, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Human dental follicle mesenchymal stem cells alleviate T cell response in inflamed tissue of Crohn's patients.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020Trial
- The role of PD-1/PD-L1 pathway in ulcerative colitis and changes following tonsil-derived mesenchymal stem cells treatment.The Korean journal of internal medicine · 2024Article
- Research progress of autoimmune diseases based on induced pluripotent stem cells.Frontiers in immunology · 2024Review
- Three-dimensional culture method enhances the therapeutic efficacies of tonsil-derived mesenchymal stem cells in murine chronic colitis model.Scientific reports · 2021Article
- Conditioned secretome of adipose-derived stem cells improves dextran sulfate sodium-induced colitis in mice.World journal of gastroenterology · 2021Article
- Umbilical cord blood mononuclear cell therapy induces clinical remission of steroid-dependent or -resistant ulcerative colitis patients.Oncotarget · 2018Article
- Genetically‑modified stem cells in treatment of human diseases: Tissue kallikrein (KLK1)‑based targeted therapy (Review).International journal of molecular medicine · 2018Review
- Stem cells for luminal, fistulizing, and perianal inflammatory bowel disease: a comprehensive updated review of the literature.Stem cells and cloning : advances and applications · 2018Review
- Tranexamic Acid and Supportive Measures to Treat Wasting Marmoset Syndrome.Comparative medicine · 2016Article
- Mesenchymal stromal cell-based therapy: Regulatory and translational aspects in gastroenterology.World journal of gastroenterology · 2016Review
- Mesenchymal Stromal Cells Mitigate Experimental Colitis via Insulin-like Growth Factor Binding Protein 7-mediated Immunosuppression.Molecular therapy : the journal of the American Society of Gene Therapy · 2016Article
- Serum matrix metalloproteinase 9 (MMP9) as a biochemical marker for wasting marmoset syndrome.The Journal of veterinary medical science · 2016Article
- Flexible Endoscopic Spray Application of Respiratory Epithelial Cells as Platform Technology to Apply Cells in Tubular Organs.Tissue engineering. Part C, Methods · 2016Article
- Successful outcome with second hematopoietic stem cell transplantation in a patient with IL-10R deficiency.Bone marrow transplantation · 2016Article
- Modern stem cell therapy: approach to disease.Wiener klinische Wochenschrift · 2015Review
- Current stage in inflammatory bowel disease: What is next?World journal of gastroenterology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammatory bowel diseases are inflammatory, chronic and progressive diseases of the intestinal tract for which no curative treatment is available. Research in other fields with stem cells of different sources and with immunoregulatory cells (regulatory T-lymphocytes and dendritic T-cells) opens up new expectations for their use in these diseases. The goal for stem cell-based therapy is to provide a permanent cure. To achieve this, it will be necessary to obtain a cellular product, original or genetically modified, that has a high migration capacity and homes into the intestine, has high survival after transplantation, regulates the immune reaction while not being visible to the patient's immune system, and repairs the injured tissue.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.