Evidence map›Paper›PMID 25815042›Full record

ArticleComputational and mathematical methods in medicine2015

A clinical decision support system for the diagnosis, fracture risks and treatment of osteoporosis.

Bjarni V Halldorsson, Aron Hjalti Bjornsson, Haukur Tyr Gudmundsson, Elvar Orn Birgisson, Bjorn Runar Ludviksson, Bjorn Gudbjornsson

Erratum issuedAbstract read
In one paragraph

Article in Computational and mathematical methods in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Complex interventions can increase osteoporosis investigations and treatment: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Digital health interventions for osteoporosis and post-fragility fracture care.Therapeutic advances in musculoskeletal disease · 2022
    Review
  6. Article
  7. Advances in automated tongue diagnosis techniques.Integrative medicine research · 2019
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Bjarni V HalldorssonInstitute of Biomedical and Neural Engineering, School of Science and Engineering, Reykjavik University, 101 Reykjavik, Iceland.
Aron Hjalti BjornssonCentre for Rheumatology Research, University Hospital, 101 Reykjavik, Iceland ; Faculty of Medicine, Debrecen University, Debrecen 4032, Hungary.
Haukur Tyr GudmundssonCentre for Rheumatology Research, University Hospital, 101 Reykjavik, Iceland ; Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland.
Elvar Orn BirgissonOsteoporosis Clinic, Akureyri Hospital, 600 Akureyri, Iceland.
Bjorn Runar LudvikssonFaculty of Medicine, University of Iceland, 101 Reykjavik, Iceland ; Department of Immunology, University Hospital, 101 Reykjavik, Iceland.
Bjorn GudbjornssonCentre for Rheumatology Research, University Hospital, 101 Reykjavik, Iceland ; Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland.ORCID 0000-0003-4631-6505

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Expanding medical knowledge increases the potential risk of medical errors in clinical practice. We present, OPAD, a clinical decision support system in the field of the medical care of osteoporosis. We utilize clinical information from international guidelines and experts in the field of osteoporosis. Physicians are provided with user interface to insert standard patient data, from which OPAD provides instant diagnostic comments, 10-year risk of fragility fracture, treatment options for the given case, and when to offer a follow-up DXA-evaluation. Thus, the medical decision making is standardized according to the best expert knowledge at any given time. OPAD was evaluated in a set of 308 randomly selected individuals. OPAD's ten-year fracture risk computation is nearly identical to FRAX (r = 0.988). In 58% of cases OPAD recommended DXA evaluation at the present time. Following a DXA measurement in all individuals, 71% of those that were recommended to have DXA at the present time received recommendation for further investigation or specific treatment by the OPAD. In only 5.9% of individuals in which DXA was not recommended, the result of the BMD measurement changed the recommendations given by OPAD.

Indexed as

Decision Support Systems, ClinicalAdolescentAdultAgedAged, 80 and overBone DensityClinical Decision-MakingExpert SystemsFemaleHumansMaleMedical InformaticsMiddle AgedOsteoporosisOsteoporotic FracturesProbability

Identifiers

PMID25815042
PMCPMC4359799

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.