ArticleFrontiers in microbiology2015
Selective pressure of antibiotics on ARGs and bacterial communities in manure-polluted freshwater-sediment microcosms.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.
- Contributions and Challenges of High Throughput qPCR for Determining Antimicrobial Resistance in the Environment: A Critical Review.Molecules (Basel, Switzerland) · 2019Pooled it
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- Bacterial diversity, quantitative risk assessment of spring waterborne pathogens and their biocontrol through phyto-biosorbents.PloS one · 2026Article
- Pulsed antibiotic release into the environment may foster the spread of antimicrobial resistance.FEMS microbiology ecology · 2025Article
- Efficient phenol removal by δ-MnOiScience · 2025Article
- Bedside Risk Scoring for Carbapenem-Resistant Gram-Negative Bacterial Infections in Patients with Hematological Malignancies.Infectious disease reports · 2025Article
- The Role of Water as a Reservoir for Antibiotic-Resistant Bacteria.Antibiotics (Basel, Switzerland) · 2025Review
- Metagenomics insights into bacterial diversity and antibiotic resistome of the sewage in the city of Belém, Pará, Brazil.Frontiers in microbiology · 2024Article
- Prevalence of Antibiotic-Resistant Pathogenic Bacteria and Level of Antibiotic Residues in Hospital Effluents in Selangor, Malaysia: Protocol for a Cross-sectional Study.JMIR research protocols · 2023Article
- Antimicrobial Resistance and Its Drivers-A Review.Antibiotics (Basel, Switzerland) · 2022Review
- Anti-Virulence Activity of 3,3'-Diindolylmethane (DIM): A Bioactive Cruciferous Phytochemical with Accelerated Wound Healing Benefits.Pharmaceutics · 2022Article
- Removal of antibiotic thiamphenicol by bacterium Aeromonas hydrophila HS01.World journal of microbiology & biotechnology · 2022Article
- Environmental hotspots for antibiotic resistance genes.MicrobiologyOpen · 2021Review
- Gain and loss of antibiotic resistant genes in multidrug resistant bacteria: One Health perspective.Journal of microbiology (Seoul, Korea) · 2021Review
- Eugenol-Functionalized Magnetite Nanoparticles Modulate Virulence and Persistence inMolecules (Basel, Switzerland) · 2021Article
- Epidemic and molecular characterization of fluoroquinolone-resistant Shigella dysenteriae 1 isolates from calves with diarrhea.BMC microbiology · 2021Article
- Analysis of Antibiotic Resistance Genes, Environmental Factors, and Microbial Community From Aquaculture Farms in Five Provinces, China.Frontiers in microbiology · 2021Article
- Global trends in antimicrobial use in aquaculture.Scientific reports · 2020Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to investigate selective pressure of antibiotics on antibiotic resistance genes (ARGs) and bacterial communities in manure-polluted aquatic environment. Three treatment groups were set up in freshwater-sediment microcosms: tetracyclines group, sulfonamides group and fluoroquinolones group. Sediment and water samples were collected on day 14 after treatment. Antibiotic concentrations, ARGs abundances and bacterial community composition were analyzed. Antibiotic concentrations were determined by ultra-performance liquid chromatography-electrospray tandem mass spectrometry. ARGs abundances were quantified by real time quantitative PCR. Bacterial community composition was analyzed based on amplicon sequencing. Of the three classes of antibiotics analyzed in the treatment groups, accumulation amounts were tetracyclines> fluoroquinolone> sulfonamides in the sediment samples, while they were sulfonamides> fluoroquinolone> tetracyclines in the water samples. In the treatment groups, the relative abundances of some tet resistance genes [tet(W) and tet(X)] and plasmid-mediated quinolone resistance (PMQR) genes [oqx(B) and aac(6')-Ib] in sediment samples were significantly higher than those in the paired water samples. Tetracyclines significantly selected the bacterial classes including Gammaproteobacteria, Clostridia, and the genera including Salmonella, Escherichia/Shigella, Clostridium, Stenotrophomonas in sediment samples. The significant selection on bacterial communities posed by sulfonamides and fluoroquinolones was also observed. The results indicated that sediment may supply an ideal setting for maintenance and persistence of tet resistance genes [tet(W) and tet(X)] and PMQR genes [oqx(B) and aac(6')-Ib] under antibiotic pollution. The results also highlighted that antibiotics significantly selected specific bacterial communities including the taxa associated with opportunistic pathogens.
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