Evidence map›Paper›PMID 25814443›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2015

Guideline sheets on the side effects of anticancer drugs are useful for general practitioners.

Marie-Eve Rouge-Bugat, Donia Lassoued, Joy Bacrie, Nathalie Boussier, Jean-Pierre Delord, Stéphane Oustric, Eric Bauvin, Maryse Lapeyre-Mestre, François Bertucci, Pascale Grosclaude

Abstract readClinical TrialMulticenter Study
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Observational
  4. Article
  5. Small Private Online Course in Teaching Oncology-Feedback After 1 Year: What Lessons?Journal of cancer education : the official journal of the American Association for Cancer Education · 2021
    Article
  6. Article
  7. Febrile neutropenia in adjuvant and neoadjuvant chemotherapy for breast cancer: a retrospective study in routine clinical practice from a single institution.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Marie-Eve Rouge-BugatDépartement Universitaire de Médecine Générale, 133 route de Narbonne, 31062, Toulouse, France. marieeve.rouge-bugat@dumg-toulouse.fr.
Donia LassouedDépartement Universitaire de Médecine Générale, 133 route de Narbonne, 31062, Toulouse, France.
Joy BacrieDépartement Universitaire de Médecine Générale, 133 route de Narbonne, 31062, Toulouse, France.
Nathalie BoussierDépartement Universitaire de Médecine Générale, 133 route de Narbonne, 31062, Toulouse, France.
Jean-Pierre DelordInstitut Universitaire du Cancer IUCT-Oncopole, 1, avenue Irène Joliot-Curie, 31059, Toulouse, Cedex 9, France.
Stéphane OustricDépartement Universitaire de Médecine Générale, 133 route de Narbonne, 31062, Toulouse, France.
Eric BauvinRéseau Régional de Cancérologie Oncomip, IUCT-Oncopole, 1, avenue Irène Joliot-Curie, 31059, Toulouse, Cedex 9, France.
Maryse Lapeyre-MestreFaculté de Médecine, UMR 1027 INSERM-UPS, 37 Allées Jules Guesde, 31000, Toulouse, France.
François BertucciDépartement d'Oncologie Médicale, Institut Paoli-Calmettes, 232, Boulevard de Sainte-Marguerite, 13009, Marseille, France.
Pascale GrosclaudeFaculté de Médecine, UMR 1027 INSERM-UPS, 37 Allées Jules Guesde, 31000, Toulouse, France.
Institut universitaire du cancer de Toulouse Oncopole · FRUniversité Toulouse III - Paul Sabatier · FRInstitut Paoli-Calmettes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeGeneral practitioners (GPs) are more and more involved in the treatment of cancer patients but feel not informed enough about anticancer treatments and associated side effects. Better communication with treatment centers is needed. We hypothesized that information sheets could improve communication.

methodsThis prospective, multicentric, and interventionist study aimed at implementing and assessing therapeutic sheets describing the side effects of anticancer drugs used for digestive and gynecological cancers and their recommended management. GPs' phone interviews were done through three successive phases and two independent cohorts. The first phase (T1; 242 GPs with one patient recently treated) listed their expectations, the second (T2; 158 GPs with one patient beginning treatment) assessed the GPs' opinion regarding the sheets, and the third (T3; responder GPs 4 months after the start of T2) assessed their usefulness in practice.

resultsIn T1, 94% of GPs declared their need of having information sheets, notably for the management of side effects. Thirty-one one-page sheets were created. In T2, 83.5% gave a favorable opinion about sheets and 80% envisaged their use in the case of side effect. In T3, 56% of GPs whose patient had experienced a side effect had used successfully the sheets for its management, and 21% of patients with side effect were hospitalized. A strong correlation existed between the use of the sheet by GPs and the hospitalization (OR 7.35 in the case of no use vs use).

conclusionThe guideline sheets represent a simple and low-cost solution to help GPs managing drugs' side effects and perhaps decrease the rate of unplanned hospitalizations.

Indexed as

Practice Guidelines as TopicAdultAgedAntineoplastic AgentsCommunicationFemaleGeneral PractitionersHumansMaleMiddle AgedNeoplasmsPhysician-Patient RelationsPilot ProjectsProspective StudiesAntineoplastic AgentsCancer treatmentDigestive cancerGeneral practiceGuidelines sheetsGynecological cancerSide effects

Identifiers

PMID25814443
OpenAlexW2033482661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.