ArticleBurns : journal of the International Society for Burn Injuries2015
Acute discrimination between superficial-partial and deep-partial thickness burns in a preclinical model with laser speckle imaging.
Article in Burns : journal of the International Society for Burn Injuries, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Article
- Comprehensive validation of a compact laser speckle contrast imaging system for vascular function assessment: from the laboratory to the clinic.Medical & biological engineering & computing · 2025Article
- The paradoxical activity of BRAF inhibitors: potential use in wound healing.Archives of dermatological research · 2025Review
- Thymoquinone-Incorporated CollaGee Biomatrix: A Promising Approach for Full-Thickness Wound Healing.Pharmaceutics · 2024Article
- A New Ex Vivo Human Skin Burn Model.Journal of burn care & research : official publication of the American Burn Association · 2024Article
- Non-invasive medical imaging technology for the diagnosis of burn depth.International wound journal · 2024Review
- Cortical Anoxic Spreading Depolarization During Cardiac Arrest is Associated with Remote Effects on Peripheral Blood Pressure and Postresuscitation Neurological Outcome.Neurocritical care · 2022Article
- [Research advances on the techniques for diagnosing burn wound depth].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022Article
- Application of contrast-enhanced ultrasound in the diagnosis of burn depth.Annals of translational medicine · 2021Article
- Extendable, large-field multi-modal optical imaging system for measuring tissue hemodynamics.Biomedical optics express · 2020Article
- Clinical applications of laser speckle contrast imaging: a review.Journal of biomedical optics · 2019Review
- Improving the histologic characterization of burn depth.Journal of cutaneous pathology · 2017Article
- Momentum transfer Monte Carlo for the simulation of laser speckle imaging and its application in the skin.Biomedical optics express · 2017Article
- Quantitative long-term measurements of burns in a rat model using Spatial Frequency Domain Imaging (SFDI) and Laser Speckle Imaging (LSI).Lasers in surgery and medicine · 2017Article
- Imaging Techniques for Clinical Burn Assessment with a Focus on Multispectral Imaging.Advances in wound care · 2016Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
A critical need exists for a robust method that enables early discrimination between superficial-partial and deep-partial thickness burn wounds. In this study, we report on the use of laser speckle imaging (LSI), a simple, non-invasive, optical imaging modality, to measure acute blood flow dynamics in a preclinical burn model. We used a heated brass comb to induce burns of varying severity to nine rats and collected raw speckle reflectance images over the course of three hours after burn. We induced a total of 12 superficial-partial and 18 deep-partial thickness burn wounds. At 3h after burn we observed a 28% and 44% decrease in measured blood flow for superficial-partial and deep-partial thickness burns, respectively, and that these reductions were significantly different (p=0.00007). This preliminary data suggests the potential role of LSI in the clinical management of burn wounds.
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