ArticleBMC musculoskeletal disorders2015
Dynamic Intraligamentary Stabilization (DIS) for treatment of acute anterior cruciate ligament ruptures: case series experience of the first three years.
Article in BMC musculoskeletal disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.
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Who cites it
49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Arthroscopic primary repair of proximal anterior cruciate ligament tears seems safe but higher level of evidence is needed: a systematic review and meta-analysis of recent literature.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020Pooled it
- Dynamic intraligamentary stabilization for ACL repair: a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019Pooled it
- Self-reported functional recovery after reconstruction versus repair in acute anterior cruciate ligament rupture (ROTOR): a randomized controlled clinical trial.BMC musculoskeletal disorders · 2018Trial
- Patient and surgical characteristics that affect revision risk in dynamic intraligamentary stabilization of the anterior cruciate ligament.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018Trial
- Changes in gait pattern and early functional results after ACL repair are comparable to those of ACL reconstruction.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018Trial
- Stress MRI assessment of partial anterior cruciate ligament injury based on three-dimensional analysis.Quantitative imaging in medicine and surgery · 2026Article
- Dynamic Intraligamentary Stabilization (DIS) Repair for ACL Ruptures in Pediatric and Adolescent Patients: An Initial Pilot Study with Long-Term Follow Up.Children (Basel, Switzerland) · 2026Article
- Conservative Management of Acute Anterior Cruciate Ligament Rupture in Recreational Athletes: A Pilot Case Series.Cureus · 2026Article
- Primary Arthroscopic Repair of Chronic Anterior Cruciate Ligament Tears.Arthroscopy techniques · 2025Article
- Successful ACL repair by dynamic intraligamentary stabilisation is non-inferior in functional performance and worse in proprioception compared to healthy controls in a case-matched study.Journal of experimental orthopaedics · 2024Article
- Reconstruction of the anterior cruciate ligament: a historical view.Annals of translational medicine · 2023Review
- Promising functional outcomes following anterior cruciate ligament repair with suture augmentation.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Spontaneous healing of acute ACL ruptures: rate, prognostic factors and short-term outcome.Archives of orthopaedic and trauma surgery · 2023Article
- Tissue Augmentation Techniques in the Management of Ligamentous Knee Injuries.Orthopedic research and reviews · 2023Review
- Occurrence of inadequate ACL healing after Dynamic Intraligamentary Stabilization and functional outcome-a multicentre case series.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2022Article
- Collagen wrapping and local platelet-rich fibrin do not improve the survival rates of ACL repair with dynamic intraligamentary stabilization: a retrospective case series after ≥5 years postoperatively.Journal of experimental orthopaedics · 2022Article
- Primary stability of single-stage revision reconstruction of the anterior cruciate ligament in case of failure of dynamic intraligamentary stabilization depends on implant position during ACL repair.Archives of orthopaedic and trauma surgery · 2022Article
- Correction to: Arthroscopic primary repair of proximal anterior cruciate ligament tears seems safe but higher level of evidence is needed: a systematic review and meta-analysis of recent literature.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Article
- Anterior cruciate ligament repair using dynamic intraligamentary stabilization provides a similarly successful outcome as all-inside anterior cruciate ligament reconstruction with a faster psychological recovery in moderately active patients.Joint diseases and related surgery · 2022Article
- Arthroscopic Anterior Cruciate Ligament Repair Versus Autograft Anterior Cruciate Ligament Reconstruction: A Meta-Analysis of Comparative Studies.Frontiers in surgery · 2022Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn recent years, the scientific discussion has focused on new strategies to enable a torn anterior cruciate ligament (ACL) to heal into mechanically stable scar tissue. Dynamic intraligamentary stabilization (DIS) was first performed in a pilot study of 10 patients. The purpose of the current study was to evaluate whether DIS would lead to similarly sufficient stability and good clinical function in a larger case series.
methodsAcute ACL ruptures were treated by using an internal stabilizer, combined with anatomical repositioning of torn bundles and microfracturing to promote self-healing. Clinical assessment (Tegner, Lysholm, IKDC, and visual analogue scale [VAS] for patient satisfaction scores) and assessment of knee laxity was performed at 3, 6, 12, and 24 months. A one-sample design with a non-inferiority margin was chosen to compare the preoperative and postoperative IKDS and Lysholm scores.
results278 patients with a 6:4 male to female ratio were included. Average patient age was 31 years. Preoperative mean IKDC, Lysholm, and Tegner scores were 98.8, 99.3, and 5.1 points, respectively. The mean anteroposterior (AP) translation difference from the healthy contralateral knee was 4.7 mm preoperatively. After DIS treatment, the mean 12-month IKDC, Lysholm, and Tegner scores were 93.6, 96.2, and 4.9 points, respectively, and the mean AP translation difference was 2.3 mm. All these outcomes were significantly non-inferior to the preoperative or healthy contralateral values (p < 0.0001). Mean patient satisfaction was 8.8 (VAS 0-10). Eight ACL reruptures occurred and 3 patients reported insufficient subjective stability of the knee at the end of the study period.
conclusionsAnatomical repositioning, along with DIS and microfracturing, leads to clinically stable healing of the torn ACL in the large majority of patients. Most patients exhibited almost normal knee function, reported excellent satisfaction, and were able to return to their previous levels of sporting activity. Moreover, this strategy resulted in stable healing of all sutured menisci, which could lower the rate of osteoarthritic changes in future. The present findings support the discussion of a new paradigm in ACL treatment based on preservation and self-healing of the torn ligament.
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