Evidence map›Paper›PMID 25813667›Full record

ReviewSeminars in perinatology2015

Use of resting-state functional MRI to study brain development and injury in neonates.

Christopher D Smyser, Jeffrey J Neil

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in perinatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 88 citations in OpenAlex.

  1. Altered connectivity and network efficiency in preterm infants.Cerebral cortex (New York, N.Y. : 1991) · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Social Determinants of Health, the developing brain, and risk and resilience for psychopathology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Microvascular Ultrasound Imaging in the Neonatal Brain: From Advanced Doppler to Super-Resolution.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Towards personalized precision functional mapping in infancy.Imaging neuroscience (Cambridge, Mass.) · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Christopher D SmyserDepartment of Neurology, Division of Child Neurology, Washington University School of Medicine, 660 South Euclid Ave., St. Louis, MO 63110.
Jeffrey J NeilDepartment of Neurology, Boston Children's Hospital, 333 Longwood Ave., LO 450, Boston, MA 02115. Electronic address: jeffrey.neil@childrens.harvard.edu.
Washington University in St. Louis · US

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
PREDICTING CHILDHOOD OUTCOMES IN PRETERM INFANTS USING CEREBRAL CONNECTIVITYK02NS089852 · NINDS · WASHINGTON UNIVERSITY · PI SMYSER, CHRISTOPHER DANIEL · 2014 to 2018
$848k
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1TR000448NINDS NIH HHS K02 NS089852NINDS NIH HHS K02NS089852
6 · The paper itself

Abstract

Advances in methodology have led to expanded application of resting-state functional MRI (rs-fMRI) to the study of term and prematurely born infants during the first years of life, providing fresh insight into the earliest forms of functional cerebral development. In this review, we detail our evolving understanding of the use of rs-fMRI for studying neonates. We initially focus on the biological processes of cortical development related to resting-state network development. We then review technical issues principally affecting neonatal investigations, including the effects of subject motion during acquisition and image distortions related to magnetic susceptibility effects. We next summarize the literature in which rs-fMRI is used to study normal brain development during the early postnatal period, the effects of prematurity, and the effects of cerebral injury. Finally, we review potential future directions for the field, such as the use of complementary imaging modalities and advanced analysis techniques.

Indexed as

Magnetic Resonance ImagingBrainBrain MappingHumansImage Processing, Computer-AssistedInfant, NewbornNeural PathwaysNeuronal PlasticityRest

Identifiers

PMID25813667
PMCPMC4379452
OpenAlexW2090458482

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.