ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2015
The epidemiology and aetiology of diarrhoeal disease in infancy in southern Vietnam: a birth cohort study.
Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Incidence of diarrhoeal disease among children aged less than five years in low- and middle-income countries: a systematic review.Journal of global health · 2025Pooled it
- Consequences of Shigella infection in young children: a systematic review.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023Pooled it
- Birth Cohort Studies Assessing Norovirus Infection and Immunity in Young Children: A Review.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Pooled it
- Community-based surveillance of norovirus disease: a systematic review.BMC infectious diseases · 2017Pooled it
- A Double-blind, Randomized, Placebo-controlled Trial of Lactobacillus acidophilus for the Treatment of Acute Watery Diarrhea in Vietnamese Children.The Pediatric infectious disease journal · 2018Trial
- Metagenomic Analysis of the Gastrointestinal Phageome and Incorporated Dysbiosis in Children with Persistent Diarrhea of Unknown Etiology in Vietnam.Pathogens (Basel, Switzerland) · 2025Article
- A review and meta-analysis of non-typhoidalOne health (Amsterdam, Netherlands) · 2024Review
- Prediction of effectiveness of universal rotavirus vaccination in Southwestern Vietnam based on a dynamic mathematical model.Scientific reports · 2024Article
- Identification of knowledge gaps in whole-genome sequence analysis of multi-resistant thermotolerant Campylobacter spp.BMC genomics · 2024Article
- Prevalence, antibiotic resistance, and genomic characterisation ofMicrobial genomics · 2024Article
- Knowledge of Medical Education on Maternal and Child Primary-Care Among Physicians: A Cross-Sectional Study.International journal of public health · 2024Article
- Genome-Wide Association Studies of Diarrhea Frequency and Duration in the First Year of Life in Bangladeshi Infants.The Journal of infectious diseases · 2023Article
- Impact and effectiveness of Rotavin-M1 under conditions of routine use in two provinces in Vietnam, 2016-2021, an observational and case-control study.The Lancet regional health. Western Pacific · 2023Article
- The identification of novel immunogenic antigens as potential Shigella vaccine components.Genome medicine · 2021Article
- The Role of Maternally Acquired Antibody in Providing Protective Immunity Against Nontyphoidal Salmonella in Urban Vietnamese Infants: A Birth Cohort Study.The Journal of infectious diseases · 2019Article
- Quantifying antimicrobial access and usage for paediatric diarrhoeal disease in an urban community setting in Asia.The Journal of antimicrobial chemotherapy · 2018Article
- No Clinical Benefit of Empirical Antimicrobial Therapy for Pediatric Diarrhea in a High-Usage, High-Resistance Setting.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Observational
- A universal genome sequencing method for rotavirus A from human fecal samples which identifies segment reassortment and multi-genotype mixed infection.BMC genomics · 2017Article
- Thermophilic Campylobacter - Neglected Foodborne Pathogens in Cambodia, Laos and Vietnam.Gastroenterology & hepatology (Bartlesville, Okla.) · 2017Article
- Viral and Bacterial Etiology of Acute Diarrhea among Children under 5 Years of Age in Wuhan, China.Chinese medical journal · 2016Article
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 3 countries.
Funding
Abstract
objectivesPrevious studies indicate a high burden of diarrhoeal disease in Vietnamese children, however longitudinal community-based data on burden and aetiology are limited. The findings from a large, prospective cohort study of diarrhoeal disease in infants in southern Vietnam are presented herein.
methodsInfants were enrolled at birth in urban Ho Chi Minh City and a semi-rural district in southern Vietnam, and followed for 12 months (n=6706). Diarrhoeal illness episodes were identified through clinic-based passive surveillance, hospital admissions, and self-reports.
resultsThe minimum incidence of diarrhoeal illness in the first year of life was 271/1000 infant-years of observation for the whole cohort. Rotavirus was the most commonly detected pathogen (50% of positive samples), followed by norovirus (24%), Campylobacter (20%), Salmonella (18%), and Shigella (16%). Repeat infections were identified in 9% of infants infected with rotavirus, norovirus, Shigella, or Campylobacter, and 13% of those with Salmonella infections.
conclusionsThe minimum incidence of diarrhoeal disease in infants in both urban and semi-rural settings in southern Vietnam was quantified prospectively. A large proportion of laboratory-diagnosed disease was caused by rotavirus and norovirus. These data highlight the unmet need for a rotavirus vaccine in Vietnam and provide evidence of the previously unrecognized burden of norovirus in infants.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.