Evidence map›Paper›PMID 25812482›Full record

Trial reportContemporary clinical trials2015

The macular degeneration and aging study: Design and research protocol of a randomized trial for a psychosocial intervention with macular degeneration patients.

Silvia Sörensen, Katherine White, Wingyun Mak, Katherine Zanibbi, Wan Tang, Amanda O'Hearn, Mark T Hegel

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Perspectives on Aging-Related Preparation.Journal of elder policy · 2021
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Silvia SörensenDepartment of Ophthalmology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States. Electronic address: silvia_sorensen@urmc.rochester.edu.
Katherine WhiteAssociation for the Blind and Visually Impaired, 100 South Clinton Avenue, Rochester, NY 14620, United States. Electronic address: kwhite@abvi-goodwill.org.
Wingyun MakDepartment of Psychology, Lehman College, 250 Bedford Park Blvd West, Bronx, NY 10468, United States. Electronic address: WINGYUN.MAK@lehman.cuny.edu.
Katherine ZanibbiDepartment of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States. Electronic address: katherine_zanibbi@urmc.rochester.edu.
Wan TangDepartment of Biostatistics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States. Electronic address: wan_Tang@urmc.rochester.edu.
Amanda O'HearnDepartment of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States. Electronic address: Amanda_OHearn@urmc.rochester.edu.
Mark T HegelDepartment of Psychiatry, Geisel School of Medicine at Dartmouth, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH, United States. Electronic address: Mark.T.Hegel@Dartmouth.edu.

Funding

Postdoctoral Training in Suicide Prevention Research (supplement 2)T32MH020061 · NIMH · UNIVERSITY OF ROCHESTER · PI VAN ORDEN, KIMBERLY ALLISON · 2001 to 2025
$5.9M
CDC Injury Control Research Center for Preventing Suicide (CDC ICRC S)R49CE002093 · CE · UNIVERSITY OF ROCHESTER · PI CAINE, ERIC D. · 2012 to 2018
$5.6M
NIMH INSTITUTIONAL NATIONAL RESEARCH SERVICE AWARDT32MH018911 · NIMH · UNIVERSITY OF ROCHESTER · PI CAINE, ERIC D. · 1988 to 2012
$2.9M
Improving Care Planning and Well-being in Older Adults with Macular DegenerationR01AG032032 · NIA · UNIVERSITY OF ROCHESTER · PI SÖRENSEN, SILVIA · 2009 to 2013
$1.7M
Postdoctoral Training in Geriatric Psychiatry ResearchT32MH073452 · NIMH · UNIVERSITY OF ROCHESTER · PI LYNESS, JEFFREY M · 2005 to 2009
$798k
NCIPC CDC HHS R49 CE002093NIA NIH HHS R01 AG032032NIMH NIH HHS T32 MH018911NIMH NIH HHS T32 MH020061NIMH NIH HHS T32 MH073452
6 · The paper itself

Abstract

backgroundAge-related Macular Degeneration (AMD) is the leading cause of irreversible and predictable blindness among older adults with serious physical and mental health consequences. Visual impairment is associated with negative future outlook and depression and has serious consequences for older adults' quality of life and, by way of depression, on long-term survival. Psychosocial interventions have the potential to alleviate and prevent depression symptoms among older AMD patients.

methodsWe describe the protocol of the Macular Degeneration and Aging Study, a randomized clinical trial of a psychosocial Preventive Problem-Solving Intervention. The intervention is aimed at enhancing well-being and future planning among older adults with macular degeneration by increasing preparation for future care.

resultsAdequate randomization and therapeutic fidelity were achieved. Current retention rates were acceptable, given the vulnerability of the population. Acceptability (adherence and satisfaction) was high.

conclusionGiven the high public health significance and impact on quality of life among older adults with vision loss, this protocol contributes a valid test of a promising intervention for maintaining mental and physical health in this population.

Indexed as

AgedAged, 80 and overAgingFemaleHumansMacular DegenerationMaleMiddle AgedPatient CompliancePatient Education as TopicPatient SatisfactionProblem SolvingQuality of LifeResearch DesignSocioeconomic FactorsVision DisordersAgingFuture planningMacular degenerationPreventive problem-solvingRandomized controlled trial

Identifiers

PMID25812482
PMCPMC4450128

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.