Evidence map›Paper›PMID 25811044›Full record

ArticleTheScientificWorldJournal2015

Diarrheagenic Escherichia coli phylogroups are associated with antibiotic resistance and duration of diarrheal episode.

Susan Mosquito, Maria J Pons, Maribel Riveros, Joaquim Ruiz, Theresa J Ochoa

Open access · goldAbstract read
In one paragraph

Article in TheScientificWorldJournal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 45 citations in OpenAlex.

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  18. Multidrug-Resistant Lineage of EnterotoxigenicFrontiers in microbiology · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Susan MosquitoInstituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima 031, Peru.
Maria J PonsISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic, Universitat de Barcelona, 08036 Barcelona, Spain ; Universidad Peruana de Ciencias Aplicadas (UPC), Lima 09, Peru.
Maribel RiverosInstituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima 031, Peru.
Joaquim RuizISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic, Universitat de Barcelona, 08036 Barcelona, Spain.ORCID 0000-0002-4431-2036
Theresa J OchoaInstituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima 031, Peru ; School of Public Health, University of Texas, Houston, TX 77030, USA.
Universidad Peruana Cayetano Heredia · PEBarcelona Institute for Global Health · ESPeruvian University of Applied Sciences · PE

Funding

Role of virulence heterogeneity in acute and presistent EPEC diarrheaK01TW007405 · FIC · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI OCHOA, THERESA J · 2006 to 2009
$433k
FIC NIH HHS K01 TW007405
6 · The paper itself

Abstract

Conventionally, in Escherichia coli, phylogenetic groups A and B1 are associated with commensal strains while B2 and D are associated with extraintestinal strains. The aim of this study was to evaluate diarrheagenic (DEC) and commensal E. coli phylogeny and its association with antibiotic resistance and clinical characteristics of the diarrheal episode. Phylogenetic groups and antibiotic resistance of 369 E. coli strains (commensal strains and DEC from children with or without diarrhea) isolated from Peruvian children <1 year of age were determined by a Clermont triplex PCR and Kirby-Bauer method, respectively. The distribution of the 369 E. coli strains among the 4 phylogenetic groups was A (40%), D (31%), B1 (21%), and B2 (8%). DEC-control strains were more associated with group A while DEC-diarrhea strains were more associated with group D (P < 0.05). There was a tendency (P = 0.06) for higher proportion of persistent diarrhea (≥ 14 days) among severe groups (B2 and D) in comparison with nonsevere groups (A and B1). Strains belonging to group D presented significantly higher percentages of multidrug resistance than the rest of the groups (P > 0.01). In summary, DEC-diarrhea strains were more associated with group D than strains from healthy controls.

Indexed as

Case-Control StudiesDiarrhea, InfantileDrug Resistance, MicrobialEscherichia coliEscherichia coli InfectionsFemaleHumansInfantMalePeruPhylogenyTime FactorsVirulence

Identifiers

PMID25811044
PMCPMC4355820
OpenAlexW2034224393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.