ArticleBioMed research international2015
Establishment of hairy root cultures of Rhaponticum carthamoides (Willd.) Iljin for the production of biomass and caffeic acid derivatives.
Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 57 citations in OpenAlex.
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- Mother transformer: A High-Throughput, Cost-Effective in Planta Hairy Root Transformation Method for Cannabis.BMC biotechnology · 2025Article
- Enhancement of Rosmarinic Acid Production in Hairy Root Cultures ofInternational journal of molecular sciences · 2025Article
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- The Enhancement of Biomass Accumulation, Caffeoylquinic Acid Derivative Production, and Antioxidant Activity ofInternational journal of molecular sciences · 2025Article
- Light-Emitting Diodes and Liquid System Affect the Caffeoylquinic Acid Derivative and Flavonoid Production and Shoot Growth ofMolecules (Basel, Switzerland) · 2024Article
- Ethnomedicinal Importance of Patuletin in Medicine: Pharmacological Activities and Analytical Aspects.Endocrine, metabolic & immune disorders drug targets · 2024Review
- Production of Phenolic Compounds and Antioxidant Activity in Hairy Root Cultures ofPlants (Basel, Switzerland) · 2023Article
- Hairy Root Cultures as a Source of Phenolic Antioxidants: Simple Phenolics, Phenolic Acids, Phenylethanoids, and Hydroxycinnamates.International journal of molecular sciences · 2023Review
- Effect of Sucrose Concentration onInternational journal of molecular sciences · 2022Article
- In Vitro Strategy for the Enhancement of the Production of Bioactive Polyphenols in Transformed Roots ofInternational journal of molecular sciences · 2022Article
- Jasmonates promote enhanced production of bioactive caffeoylquinic acid derivative inPlant cell, tissue and organ culture · 2022Article
- Effects of various Agrobacterium rhizogenes strains on hairy root induction and analyses of primary and secondary metabolites in Ocimum basilicum.Frontiers in plant science · 2022Article
- Compact shoot architecture of Osteospermum fruticosum transformed with Rhizobium rhizogenes.Plant cell reports · 2021Article
- A Brief Overview of Potential Treatments for Viral Diseases Using Natural Plant Compounds: The Case of SARS-Cov.Molecules (Basel, Switzerland) · 2021Review
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- Medicinal Plants to Strengthen Immunity during a Pandemic.Pharmaceuticals (Basel, Switzerland) · 2020Review
- MeJA Elicitation of Chicory Hairy Roots Promotes Efficient Increase of 3,5-diCQA Accumulation, a Potent Antioxidant and Antibacterial Molecule.Antibiotics (Basel, Switzerland) · 2020Article
- Evaluation of Polyphenolic Compounds and Pharmacological Activities in Hairy Root Cultures ofMolecules (Basel, Switzerland) · 2019Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to obtain transformed roots of Rhaponticum carthamoides and evaluate their phytochemical profile. Hairy roots were induced from leaf explants by the transformation of Agrobacterium rhizogenes strains A4 and ATCC 15834. The best response (43%) was achieved by infection with A4 strain. The effects of different liquid media (WPM, B5, SH) with full and half-strength concentrations of macro- and micronutrients on biomass accumulation of the best grown hairy root line (RC3) at two different lighting conditions (light or dark) were investigated. The highest biomass (93 g L(-1) of the fresh weight after 35 days) was obtained in WPM medium under periodic light. UPLC-PDA-ESI-MS(3) and HPLC-PDA analyses of 80% aqueous methanol extracts from the obtained hairy roots revealed the presence of eleven caffeoylquinic acids and their derivatives and five flavonoid glycosides. The production of caffeoylquinic acids and their derivatives was elevated in hairy roots grown in the light. Only light-grown hairy roots demonstrated the capability for the biosynthesis of such flavonoid glycosides as quercetagetin, quercetin, luteolin, and patuletin hexosides. Chlorogenic acid, 3,5-di-O-caffeoylquinic acid and a tentatively identified tricaffeoylquinic acid derivative were detected as the major compounds present in the transformed roots.
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