Evidence map›Paper›PMID 25810877›Full record

ArticleIranian journal of basic medical sciences2015

Safranal-loaded solid lipid nanoparticles: evaluation of sunscreen and moisturizing potential for topical applications.

Bahman Khameneh, Vahid Halimi, Mahmoud Reza Jaafari, Shiva Golmohammadzadeh

Abstract read
In one paragraph

Article in Iranian journal of basic medical sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Current pharmaceutical design · 2026
    Review
  2. Frontiers in medicine · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Pharmacological effects of Safranal: An updated review.Iranian journal of basic medical sciences · 2023
    Review
  7. Review
  8. Review
  9. Features, applications, and sustainability of lipid nanoparticles in cosmeceuticals.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022
    Review
  10. Review
  11. Review
  12. Current developments in the nanomediated delivery of photoprotective phytochemicals.Environmental science and pollution research international · 2020
    Review
  13. Article
  14. Article
  15. Antifungal activity ofIranian journal of basic medical sciences · 2016
    Article
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bahman KhamenehDepartment of Food and Drug Control, Mashhad University of Medical Sciences, Mashhad, Iran.
Vahid HalimiSchool of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahmoud Reza JaafariBiotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Shiva GolmohammadzadehNanotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn the current study, sunscreen and moisturizing properties of solid lipid nanoparticle (SLN)-safranal formulations were evaluated. MATERIALS AND

methodsSeries of SLN were prepared using glyceryl monostearate, Tween 80 and different amounts of safranal by high shear homogenization, and ultrasound and high-pressure homogenization (HPH) methods. SLN formulations were characterized for size, zeta potential, morphology, thermal properties, and encapsulation efficacy. The Sun Protection Factor (SPF) of the products was determined in vitro using transpore tape. The moisturizing activity of the products was also evaluated by corneometer.

resultsThe SPF of SLN-safranal formulations was increased when the amount of safranal increased. Mean particle size for all formulas was approximately 106 nm by probe sonication and 233 nm using HPH method. The encapsulation efficiency of safranal was around 70% for all SLN-safranal formulations.

conclusionThe results conclude that SLN-safranal formulations were found to be effective for topical delivery of safranal and succeeded in providing appropriate sunscreen properties.

Indexed as

Moisturizing activitySaffronSafranalSolid Lipid NanoparticlesSunscreen

Identifiers

PMID25810877
PMCPMC4366744

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.