ReviewWorld journal of cardiology2015
Role of Helicobacter pylori infection in pathogenesis of atherosclerosis.
Review in World journal of cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- A Comprehensive Survey of the Relationship betweenArchives of Iranian medicine · 2022Pooled it
- Pooled it
- Metabolic reprogramming inFrontiers in cellular and infection microbiology · 2025Review
- Risk of Ischemic Stroke in Relation toGut and liver · 2024Observational
- Review
- Homocystein, Vitamin B12 and Folic Acid as Screening Biomarkers in Early Diagnosis and Gastric Cancer Monitoring.Medical sciences (Basel, Switzerland) · 2024Article
- Review
- Impact ofFrontiers in gastroenterology (Lausanne, Switzerland) · 2024Review
- The Gastric Connection: Serum Gastric Biomarkers, Metabolic Syndrome and Transition in Metabolic Status.Journal of inflammation research · 2024Article
- Infection withFrontiers in pharmacology · 2023Review
- The impact ofFrontiers in microbiology · 2023Article
- Pathophysiology of central serous chorioretinopathy: a literature review with quality assessment.Eye (London, England) · 2022Review
- Inflammation at the crossroads ofFuture microbiology · 2022Article
- Impact ofMicroorganisms · 2021Review
- On the Role of Paraoxonase-1 and Chemokine Ligand 2 (C-C motif) in Metabolic Alterations Linked to Inflammation and Disease. A 2021 Update.Biomolecules · 2021Review
- Review
- Assessing the Relationship betweenHealthcare (Basel, Switzerland) · 2021Article
- Roles of Macrophages in Atherogenesis.Frontiers in pharmacology · 2021Review
- Relationship BetweenInternational journal of general medicine · 2021Review
- Role ofJournal of clinical medicine · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Though a century old hypothesis, infection as a cause for atherosclerosis is still a debatable issue. Epidemiological and clinical studies had shown a possible association but inhomogeneity in the study population and study methods along with potential confounders have yielded conflicting results. Infection triggers a chronic inflammatory state which along with other mechanisms such as dyslipidemia, hyper-homocysteinemia, hypercoagulability, impaired glucose metabolism and endothelial dysfunction, contribute in pathogenesis of atherosclerosis. Studies have shown a positive relations between Cytotoxic associated gene-A positive strains of Helicobacter pylori and vascular diseases such as coronary artery disease and stroke. Infection mediated genetic modulation is a new emerging theory in this regard. Further large scale studies on infection and atherosclerosis focusing on multiple pathogenetic mechanisms may help in refining our knowledge in this aspect.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.