ReviewInternational journal of endocrinology2015
Evidence for the adverse effect of starvation on bone quality: a review of the literature.
Review in International journal of endocrinology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 43 citations in OpenAlex.
- Development and validation of a tool for detecting misinformation risk in diet, nutrition, and health content (Diet-MisRAT).Scientific reports · 2026Article
- Comparison of the accuracy of Cameriere's European formula with CBCT and panoramic radiography in dental age estimation in Turkish children.Forensic science, medicine, and pathology · 2026Article
- A Heavy Issue: Changes in Body Size in London Before, During and After the Black Death.American journal of biological anthropology · 2025Article
- The Current State of Knowledge on Osteoporosis in Holocaust Survivors and Their Descendants.Rambam Maimonides medical journal · 2024Review
- Bone of contention: Intra-element variability in remodelling of human femora based on histomorphometric and isotope analyses.PloS one · 2024Article
- Impacts of microgravity on amino acid metabolism during spaceflight.Experimental biology and medicine (Maywood, N.J.) · 2023Review
- Secondary Osteoporosis and Metabolic Bone Diseases.Journal of clinical medicine · 2022Review
- Dietary Complex and Slow Digestive Carbohydrates Promote Bone Mass and Improve Bone Microarchitecture during Catch-Up Growth in Rats.Nutrients · 2022Article
- Treatment of cystic fibrosis related bone disease.Journal of clinical & translational endocrinology · 2022Article
- Association of Famine Exposure on the Changing Clinical Phenotypes of Primary Hyperparathyroidism in 20 years.Frontiers in endocrinology · 2022Article
- Inflammatory stimuli alter bone marrow composition and compromise bone health in the malnourished host.Frontiers in immunology · 2022Article
- Childhood trauma determines different clinical and biological manifestations in patients with eating disorders.Eating and weight disorders : EWD · 2021Observational
- Effects of Starvation on the Levels of Triglycerides, Diacylglycerol, and Activity of Lipase in Male and Female Drosophila Melanogaster.Journal of lipids · 2021Article
- Childhood hunger experiences and chronic health conditions later in life among Brazilian older adults.Revista panamericana de salud publica = Pan American journal of public health · 2021Article
- Hibernating bear serum hinders osteoclastogenesis in-vitro.PloS one · 2020Article
- Prenatal Exposure to Famine and Risk for Development of Psychopathology in Adulthood: A Meta-Analysis.Journal of psychiatry and psychiatric disorders · 2019Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malnutrition and starvation's possible adverse impacts on bone health and bone quality first came into the spotlight after the horrors of the Holocaust and the ghettos of World War II. Famine and food restrictions led to a mean caloric intake of 200-800 calories a day in the ghettos and concentration camps, resulting in catabolysis and starvation of the inhabitants and prisoners. Severely increased risks of fracture, poor bone mineral density, and decreased cortical strength were noted in several case series and descriptive reports addressing the medical issues of these individuals. A severe effect of severely diminished food intake and frequently concomitant calcium- and Vitamin D deficiencies was subsequently proven in both animal models and the most common cause of starvation in developed countries is anorexia nervosa. This review attempts to summarize the literature available on the impact of the metabolic response to Starvation on overall bone health and bone quality.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.