Evidence map›Paper›PMID 25810660›Full record

ArticleJournal of natural science, biology, and medicine

Antibiotic susceptibility pattern of Enterobacteriaceae and non-fermenter Gram-negative clinical isolates of microbial resource orchid.

Periasamy Hariharan, Thirunavukkarasu Bharani, Jonathan Sampath Franklyne, Prithwijit Biswas, Shakti S Solanki, Maneesh Paul-Satyaseela

Open access · diamondAbstract read
In one paragraph

Article in Journal of natural science, biology, and medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Identification of plasmid encodedIranian journal of microbiology · 2025
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  5. Insights into Kinases of ESKAPE Pathogens for Therapeutic Interventions.Cardiovascular & hematological agents in medicinal chemistry · 2024
    Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Periasamy HariharanDepartment of Microbiology, Drug Discovery Research, Orchid Chemicals and Pharmaceuticals Ltd., Sholinganallur, Chennai, Tamil Nadu, India.
Thirunavukkarasu BharaniDepartment of Microbiology, Drug Discovery Research, Orchid Chemicals and Pharmaceuticals Ltd., Sholinganallur, Chennai, Tamil Nadu, India.
Jonathan Sampath FranklyneDepartment of Microbiology, Drug Discovery Research, Orchid Chemicals and Pharmaceuticals Ltd., Sholinganallur, Chennai, Tamil Nadu, India.
Prithwijit BiswasDepartment of Biotechnology, School of Biotechnology, KIIT University, Bhubaneswar, Odisha, India.
Shakti S SolankiDepartment of Microbiology, Drug Discovery Research, Orchid Chemicals and Pharmaceuticals Ltd., Sholinganallur, Chennai, Tamil Nadu, India.
Maneesh Paul-SatyaseelaDepartment of Microbiology, Drug Discovery Research, Orchid Chemicals and Pharmaceuticals Ltd., Sholinganallur, Chennai, Tamil Nadu, India.
KIIT University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicrobial resource orchid is a collection of Gram-positive and Gram-negative clinical isolates sourced from different hospitals and diagnostic laboratories in India. We determined the antibiotic susceptibility of a set of Gram-negative Enterobacteriaceae and non-fermenter clinical isolates from microbial resource orchid, collected during the period of 2002-2012 against commonly used antibiotics. MATERIALS AND

methodsA total of 247 Gram negative strains consisting of 142 Enterobacteriaceae and 105 non-fermenters from microbial resource orchid were selected for determining minimum inhibitory concentration against β-lactams, aminoglycosides, quinolone, and tetracycline by agar dilution method as per clinical and laboratory standards institute guidelines.

resultsAll the isolates had high resistance to ampicillin, piperacillin, ceftazidime, gentamicin, tetracycline, and ciprofloxacin. Pseudomonas aeruginosa showed moderate resistance to carbapenems.

conclusionThis study demonstrated the high level of antibiotic resistance among the strains collected under microbial resource orchid and further, such data and the strains can be used in new chemical entities profiling.

Indexed as

antibiotic resistanceAntibiotic susceptibilityGram-negative clinical isolatesminimum inhibitory concentration

Identifiers

PMID25810660
PMCPMC4367035
OpenAlexW1971412283

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.