ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2015
Reduced muscle lengthening during eccentric contractions as a mechanism underpinning the repeated-bout effect.
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 40 citations in OpenAlex.
- Influence of Intended Slow and Fast Eccentric Back Squat Velocity on Subsequent Countermovement Jump Performance.Journal of functional morphology and kinesiology · 2026Article
- Effect of repeated bout effect induced by eccentric exercises on joint stiffness endurance in males.Physiological reports · 2025Article
- Effects of a 7-day step taper, training cessation, and retraining on lower body physical and morphological aspects in elite female ice hockey players.Frontiers in sports and active living · 2025Article
- Increased muscle force does not induce greater stretch-induced damage to calf muscles during work-matched heel drop exercise.European journal of applied physiology · 2023Article
- Influence of specific collagen peptides and 12-week concurrent training on recovery-related biomechanical characteristics following exercise-induced muscle damage-A randomized controlled trial.Frontiers in nutrition · 2023Article
- Neuromuscular, biomechanical, and energetic adjustments following repeated bouts of downhill running.Journal of sport and health science · 2022Article
- The Relationship Between Acute Exercise-Induced Changes in Extramuscular Connective Tissue Thickness and Delayed Onset Muscle Soreness in Healthy Participants: A Randomized Controlled Crossover Trial.Sports medicine - open · 2022Article
- Muscle Shear Elastic Modulus Provides an Indication of the Protection Conferred by the Repeated Bout Effect.Frontiers in physiology · 2022Article
- Eccentric exercise per se does not affect muscle damage biomarkers: early and late phase adaptations.European journal of applied physiology · 2021Article
- Exercise induced changes in echo intensity within the muscle: a brief review.Journal of ultrasound · 2020Review
- The impact of skeletal muscle contraction on CD146American journal of physiology. Cell physiology · 2019Article
- The relationship between stiffness and pain following unaccustomed eccentric exercise: the effects of gentle stretch and repeated bout.European journal of applied physiology · 2019Article
- Effectiveness of a Home-Based Eccentric-Exercise Program on the Torque-Angle Relationship of the Shoulder External Rotators: A Pilot Study.Journal of sport rehabilitation · 2017Article
- Influence of Maturation Status on Eccentric Exercise-Induced Muscle Damage and the Repeated Bout Effect in Females.Frontiers in physiology · 2017Article
- Muscle damage and inflammation after eccentric exercise: can the repeated bout effect be removed?Physiological reports · 2015Article
- Skeletal Muscle Inflammation Following Repeated Bouts of Lengthening Contractions in Humans.Frontiers in physiology · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
This study investigated biceps brachii distal myotendinous junction (MTJ) displacement during maximal eccentric elbow flexor contractions to test the hypothesis that muscle length change would be smaller (less MTJ displacement) during the second than the first exercise bout. Ten untrained men performed two eccentric exercise bouts (ECC1 and ECC2) with the same arm consisting of 10 sets of six maximal isokinetic (60°/s) eccentric elbow flexor contractions separated by 4 wk. Biceps brachii distal MTJ displacement was assessed using B-mode ultrasonography, and changes in the displacement (muscle length change) from the start to the end of each contraction during each set and over 10 sets were compared between bouts by two-way repeated-measures ANOVA. Several indirect muscle damage markers were also measured and compared between bouts by two-way repeated-measures ANOVA. The magnitude of MTJ displacement (average of six contractions) increased from set 1 (8.2 ± 4.7 mm) to set 10 (16.4 ± 4.7 mm) during ECC1 (P < 0.05), but no significant changes over sets were evident during ECC2 (set 1: 8.5 ± 4.0 mm; set 10: 9.3 ± 3.1 mm). Changes in maximal voluntary isometric contraction strength, range of motion, muscle thickness, ultrasound echo intensity, serum creatine kinase activity, and muscle soreness (visual analog scale) were smaller (P < 0.05) following ECC2 than ECC1, showing less damage in the repeated bout. These results indicate that the magnitude of muscle lengthening was less during the second than the first eccentric exercise bout, which appears to be a mechanism underpinning the repeated-bout effect.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.