Evidence map›Paper›PMID 25810056›Full record

ReviewSchizophrenia bulletin2015

Cognition and brain function in schizotypy: a selective review.

Ulrich Ettinger, Christine Mohr, Diane C Gooding, Alex S Cohen, Alexander Rapp, Corinna Haenschel, Sohee Park

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Schizophrenia bulletin, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 3 pooled it
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 3 syntheses or guidelines pooled it, 251 citations in OpenAlex.

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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 4 countries.

Ulrich EttingerDepartment of Psychology, University of Bonn, Bonn, Germany; ulrich.ettinger@uni-bonn.de.
Christine MohrInstitute of Psychology, University of Lausanne, Lausanne, Switzerland;
Diane C GoodingDepartment of Psychology and Department of Psychiatry, University of Wisconsin-Madison, Madison, WI;
Alex S CohenDepartment of Psychology, Louisiana State University, Baton Rouge, LA;
Alexander RappDepartment of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany;
Corinna HaenschelDepartment of Psychology, City University, London, UK;
Sohee ParkDepartment of Psychology, Vanderbilt University, Nashville, TN.
City, University of London · GBLouisiana State University · USUniversity of Bonn · DEUniversity of Lausanne · CHUniversity of Tübingen · DEUniversity of Wisconsin–Madison · USVanderbilt University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizotypy refers to a set of personality traits thought to reflect the subclinical expression of the signs and symptoms of schizophrenia. Here, we review the cognitive and brain functional profile associated with high questionnaire scores in schizotypy. We discuss empirical evidence from the domains of perception, attention, memory, imagery and representation, language, and motor control. Perceptual deficits occur early and across various modalities. While the neural mechanisms underlying visual impairments may be linked to magnocellular dysfunction, further effects may be seen downstream in higher cognitive functions. Cognitive deficits are observed in inhibitory control, selective and sustained attention, incidental learning, and memory. In concordance with the cognitive nature of many of the aberrations of schizotypy, higher levels of schizotypy are associated with enhanced vividness and better performance on tasks of mental rotation. Language deficits seem most pronounced in higher-level processes. Finally, higher levels of schizotypy are associated with reduced performance on oculomotor tasks, resembling the impairments seen in schizophrenia. Some of these deficits are accompanied by reduced brain activation, akin to the pattern of hypoactivations in schizophrenia spectrum individuals. We conclude that schizotypy is a construct with apparent phenomenological overlap with schizophrenia and stable interindividual differences that covary with performance on a wide range of perceptual, cognitive, and motor tasks known to be impaired in schizophrenia. The importance of these findings lies not only in providing a fine-grained neurocognitive characterization of a personality constellation known to be associated with real-life impairments, but also in generating hypotheses concerning the aetiology of schizophrenia.

Indexed as

BrainCognition DisordersExecutive FunctionHumansPerceptual DisordersPsychomotor PerformanceSchizotypal Personality Disorderattentionimagerylanguagememorymovementperceptionpersonalityschizophrenia

Identifiers

PMID25810056
PMCPMC4373634
OpenAlexW2031519797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.