Evidence map›Paper›PMID 25809794›Full record

ArticleNeurogastroenterology and motility2015

Inpatient burden of childhood functional GI disorders in the USA: an analysis of national trends in the USA from 1997 to 2009.

R Park, S Mikami, J LeClair, A Bollom, C Lembo, S Sethi, A Lembo, M Jones, V Cheng, E Friedlander and 1 more

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurogastroenterology and motility, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05981300 (GpCRC Pediatric Gastroparesis Registry 2), which is not on this map. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05981300 recruitingnot on this mapstarted 2024, after this paper: background citation

GpCRC Pediatric Gastroparesis Registry 2: Characterization and Clinical Course of Symptoms and Gastric Emptying in Pediatric, Adolescent, and Young Adult Participants With Symptoms of Gastroparesis

Typeobservational_patient_registrySponsorJohns Hopkins Bloomberg School of Public HealthRan2024 to 2027Enrolled216ConditionsGastroparesis, Gastroparesis-like Syndrome
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 94 citations in OpenAlex.

  1. Pooled it
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  16. Article
  17. Myths and misconceptions about childhood constipation.European journal of pediatrics · 2023
    Review
  18. Article
  19. Article
  20. A comprehensive review of functional dyspepsia in pediatrics.Clinical journal of gastroenterology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

R ParkDivision of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
S Mikami
J LeClair
A Bollom
C Lembo
S Sethi
A Lembo
M Jones
V Cheng
E Friedlander
S Nurko
Beth Israel Deaconess Medical Center · USBoston Children's Museum · USMacquarie University · AU

Funding

Efficacy of Open-Label Placebo, Double-Blind Placebo, and Peppermint Oil in IBSR01AT008573 · NCCIH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KAPTCHUK, TED, LEMBO, ANTHONY J · 2015 to 2019
$4.3M
Patient Oriented Research in Pediatric Motility and Related DisordersK24DK082792 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI NURKO, SAMUEL · 2009 to 2013
$923k
CHARACTERIZATION OF HEPATIC GLUCOSE PRODUCTION IN SITUF32DK008279 · NIDDK · CORNELL UNIVERSITY ITHACA · PI CANFIELD, WESLEY K · 1988 to 1990
–
NCCIH NIH HHS R01 AT008573NIDDK NIH HHS K24 DK082792NIDDK NIH HHS K24DK082792A
6 · The paper itself

Abstract

backgroundFunctional gastrointestinal disorders (FGIDs) are among the most common outpatient diagnoses in pediatric primary care and gastroenterology. There is limited data on the inpatient burden of childhood FGIDs in the USA. The aim of this study was to evaluate the inpatient admission rate, length of stay (LoS), and associated costs related to FGIDs from 1997 to 2009.

methodsWe analyzed the Kids' Inpatient Sample Database (KID) for all subjects in which constipation (ICD-9 codes: 564.0-564.09), abdominal pain (ICD-9 codes: 789.0-789.09), irritable bowel syndrome (IBS) (ICD-9 code: 564.1), abdominal migraine (ICD-9 code: 346.80 and 346.81) dyspepsia (ICD-9 code: 536.8), or fecal incontinence (ICD-codes: 787.6-787.63) was the primary discharge diagnosis from 1997 to 2009. The KID is the largest publicly available all-payer inpatient database in the USA, containing data from 2 to 3 million pediatric hospital stays yearly. KEY

resultsFrom 1997 to 2009, the number of discharges with a FGID primary diagnosis increased slightly from 6,348,537 to 6,393,803. The total mean cost per discharge increased significantly from $6115 to $18,058 despite the LoS remaining relatively stable. Constipation and abdominal pain were the most common FGID discharge diagnoses. Abdominal pain and abdominal migraine discharges were most frequent in the 10-14 year age group. Constipation and fecal incontinence discharges were most frequent in the 5-9 year age group. IBS discharge was most common for the 15-17 year age group. CONCLUSIONS & INFERENCES: Hospitalizations and associated costs in childhood FGIDs have increased in number and cost in the USA from 1997 to 2009. Further studies to determine optimal methods to avoid unnecessary hospitalizations and potentially harmful diagnostic testing are indicated.

Indexed as

Hospital CostsAbdominal PainAdolescentChildChild, PreschoolConstipationDyspepsiaFecal IncontinenceFemaleGastrointestinal DiseasesHospitalizationHumansIrritable Bowel SyndromeLength of StayMaleUnited Statesabdominal painassociated costsconstipationdyspepsiaepidemiologyfecal incontinencefunctional GI disordersinpatient admission rateslength of staypediatric

Identifiers

PMID25809794
PMCPMC5549670
OpenAlexW2115461311

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.