Evidence map›Paper›PMID 25809732›Full record

ReviewCNS neuroscience & therapeutics2015

Neuropsychological and neuroimaging characteristics of amnestic mild cognitive impairment subtypes: a selective overview.

Xin Li, Zhan-Jun Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in CNS neuroscience & therapeutics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Brain network dynamics in patients with single- and multiple-domain amnestic mild cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
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  8. A non-linear relationship between blood pressure and mild cognitive impairment in elderly individuals: A cohort study based on the Chinese longitudinal healthy longevity survey (CLHLS).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Article
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  16. Imaging brain networks in neurodegenerative diseases.CNS neuroscience & therapeutics · 2015
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xin LiState Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Zhan-Jun ZhangState Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive age-related neurodegenerative disease. Amnestic mild cognitive impairment (aMCI) is considered to represent early AD. Various aMCI clinical subtypes have been identified as either single domain (SD) or multidomain (MD). The various subtypes represent heterogeneous syndrome, indicating the different probability of progression to AD. Understanding the heterogeneous concept of aMCI can help to construct potential biomarkers to monitor the progression of aMCI to AD. This review provides an overview of various neuroimaging measures for subtypes of aMCI. Focusing on neuropsychological, structural, and functional neuroimaging findings, we found that aMCI showed differences in clinical progression and the abnormalities in MD-aMCI were distributed across temporal, frontal, and parietal cortices, which is similar to AD. This is also compatible with the notion that MD-aMCI is a transition stage between SD-aMCI and AD. Our review provided a framework for the diagnosis of clinical subtypes of aMCI and early detection and intervention of the progression from aMCI to AD.

Indexed as

AmnesiaBrainCognitive DysfunctionHumansNeuroimagingNeuropsychological TestsAlzheimer's diseaseAmnestic mild cognitive impairmentAmyloid PETfMRIMorphology

Identifiers

PMID25809732
PMCPMC6493200

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.