Evidence map›Paper›PMID 25809512›Full record

ArticleInternational journal of environmental research and public health2015

Monoamine oxidase a promoter variable number of tandem repeats (MAOA-uVNTR) in alcoholics according to Lesch typology.

Agnieszka Samochowiec, Magdalena Chęć, Edyta Kopaczewska, Jerzy Samochowiec, Otto Lesch, Elżbieta Grochans, Andrzej Jasiewicz, Przemyslaw Bienkowski, Kołodziej Łukasz, Anna Grzywacz

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Agnieszka SamochowiecInstitute of Psychology, Department of Clinical Psychology, University of Szczecin, Krakowska 69, 71-017 Szczecin, Poland. samoaga@tlen.pl.
Magdalena ChęćInstitute of Psychology, Department of Clinical Psychology, University of Szczecin, Krakowska 69, 71-017 Szczecin, Poland. magda.chec@gmail.com.
Edyta KopaczewskaUniversity Center for Education, University of Szczecin, Szwoleżerów 18a, 71-062 Szczecin, Poland. edi55@wp.pl.
Jerzy SamochowiecDepartment of Psychiatry, Pomeranian Medical University, Broniewskiego 26, 71-460 Szczecin, Poland. samoj@pum.edu.pl.
Otto LeschDepartment of Psychiatry, Vienna University, Waehringer Guertel 18-20, A-1090 Vienna, Austria. otto-michael.lesch@meduniwien.ac.at.
Elżbieta GrochansDepartment of Nursing, Pomeranian Medical University, Żołnierska 48, 71-210 Szczecin, Poland. grochans@pum.edu.pl.
Andrzej JasiewiczDepartment of Psychiatry, Pomeranian Medical University, Broniewskiego 26, 71-460 Szczecin, Poland. andrzej.jasiewicz@gmail.com.
Przemyslaw BienkowskiInstitute of Psychiatry and Neurology, Department of Pharmacology, Sobieskiego 9, 02-957 Warszawa, Poland. bienkow@ipin.edu.pl.
Kołodziej ŁukaszDepartment of Orthopedics, Pomeranian Medical University, Unii Lubelskiej 1, 71-460 Szczecin, Poland. Lukas@hot.pl.
Anna GrzywaczDepartment of Psychiatry, Pomeranian Medical University, Broniewskiego 26, 71-460 Szczecin, Poland. annagrzywacz@gazeta.pl.
Pomeranian Medical University · PLUniversity of Szczecin · PLInstitute of Psychiatry and Neurology · PLUniversity of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to examine the association between the MAOA-uVNTR gene polymorphism in a homogeneous subgroups of patients with alcohol dependence categorized according to Lesch's typology.

methodsDNA was provided from alcohol dependent (AD) patients (n=370) and healthy control subjects (n=168) all of Polish descent. The history of alcoholism was obtained using the Polish version of the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA). Samples were genotyped using PCR methods.

resultsWe found no association between alcohol dependence and MAOA gene polymorphism.

conclusionsLesch typology is a clinical consequence of the disease and its phenotypic description is too complex for a simple genetic analysis.

Indexed as

Minisatellite RepeatsPolymorphism, GeneticPromoter Regions, GeneticAdultAlcoholismCase-Control StudiesFemaleGenetic MarkersGenotypeHumansMaleMiddle AgedMonoamine OxidaseGenetic MarkersMonoamine Oxidasemonoamine oxidase A, human

Identifiers

PMID25809512
PMCPMC4377966
OpenAlexW2020920747

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.