ArticlePlanta2015
A gene co-expression network predicts functional genes controlling the re-establishment of desiccation tolerance in germinated Arabidopsis thaliana seeds.
Article in Planta, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 63 citations in OpenAlex.
- Over-expression transcription factor ERF1 promotes seed germination by enhancing mitochondrial function.Plant cell reports · 2026Article
- Transcription factor ERF1 promotes seed germination by repressing jasmonic acid (JA) signaling pathway.Plant cell reports · 2025Article
- Critical radicle length window governing loss of dehydration tolerance in germinated Perilla seeds: insights from physiological and transcriptomic analyses.BMC plant biology · 2024Article
- Transcriptomic Analysis of the Dehydration Rate of Mature Rice (International journal of molecular sciences · 2023Article
- SeedTransNet: a directional translational network revealing regulatory patterns during seed maturation and germination.Journal of experimental botany · 2023Article
- Mechanism of [COInternational journal of molecular sciences · 2022Article
- Multi-Omics Approaches and Resources for Systems-Level Gene Function Prediction in the Plant Kingdom.Plants (Basel, Switzerland) · 2022Review
- Changes in genotoxic stress response, ribogenesis and PAP (3'-phosphoadenosine 5'-phosphate) levels are associated with loss of desiccation tolerance in overprimed Medicago truncatula seeds.Plant, cell & environment · 2022Article
- Mechanistic insights derived from re-establishment of desiccation tolerance in germinating xerophytic seeds:Frontiers in plant science · 2022Review
- Chromatin dynamics associated with seed desiccation tolerance/sensitivity at early germination inFrontiers in plant science · 2022Article
- The Orthodox Dry Seeds Are Alive: A Clear Example of Desiccation Tolerance.Plants (Basel, Switzerland) · 2021Review
- Article
- ArabidopsisInternational journal of molecular sciences · 2021Article
- Transition from Seeds to Seedlings: Hormonal and Epigenetic Aspects.Plants (Basel, Switzerland) · 2021Review
- Gene co-expression analysis of tomato seed maturation reveals tissue-specific regulatory networks and hubs associated with the acquisition of desiccation tolerance and seed vigour.BMC plant biology · 2021Article
- RabA2b Overexpression Alters the Plasma-Membrane Proteome and Improves Drought Tolerance in Arabidopsis.Frontiers in plant science · 2021Article
- Molecular Signatures and Networks of Cardiomyocyte Differentiation in Humans and Mice.Molecular therapy. Nucleic acids · 2020Article
- Induction of desiccation tolerance in desiccation sensitive Citrus limon seeds.Journal of integrative plant biology · 2019Article
- A Co-Expression Network in Hexaploid Wheat Reveals Mostly Balanced Expression and Lack of Significant Gene Loss of Homeologous Meiotic Genes Upon Polyploidization.Frontiers in plant science · 2019Article
- Dehiscence method: a seed-saving, quick and simple viability assessment in rice.Plant methods · 2018Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MAIN
conclusionDuring re-establishment of desiccation tolerance (DT), early events promote initial protection and growth arrest, while late events promote stress adaptation and contribute to survival in the dry state. Mature seeds of Arabidopsis thaliana are desiccation tolerant, but they lose desiccation tolerance (DT) while progressing to germination. Yet, there is a small developmental window during which DT can be rescued by treatment with abscisic acid (ABA). To gain temporal resolution and identify relevant genes in this process, data from a time series of microarrays were used to build a gene co-expression network. The network has two regions, namely early response (ER) and late response (LR). Genes in the ER region are related to biological processes, such as dormancy, acquisition of DT and drought, amplification of signals, growth arrest and induction of protection mechanisms (such as LEA proteins). Genes in the LR region lead to inhibition of photosynthesis and primary metabolism, promote adaptation to stress conditions and contribute to seed longevity. Phenotyping of 12 hubs in relation to re-establishment of DT with T-DNA insertion lines indicated a significant increase in the ability to re-establish DT compared with the wild-type in the lines cbsx4, at3g53040 and at4g25580, suggesting the operation of redundant and compensatory mechanisms. Moreover, we show that re-establishment of DT by polyethylene glycol and ABA occurs through partially overlapping mechanisms. Our data confirm that co-expression network analysis is a valid approach to examine data from time series of transcriptome analysis, as it provides promising insights into biologically relevant relations that help to generate new information about the roles of certain genes for DT.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.