Evidence map›Paper›PMID 25808967›Full record

ArticleThe Journal of the American Academy of Orthopaedic Surgeons2015

Molecular diagnostics.

Hyonmin Choe, Carl A Deirmengian, Noreen J Hickok, Tiffany N Morrison, Rocky S Tuan

Open access · greenAbstract read
In one paragraph

Article in The Journal of the American Academy of Orthopaedic Surgeons, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Detection ofBioMed research international · 2022
    Article
  5. Article
  6. Article
  7. Serum interleukin 6 could be a valuable initial diagnostic tool in prosthetic knee joint infections.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2019
    Article
  8. A Real Pain: Diagnostic Quandaries and Septic Arthritis.Journal of clinical microbiology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hyonmin Choe
Carl A Deirmengian
Noreen J Hickok
Tiffany N Morrison
Rocky S Tuan
Rothman Institute · US

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
Creating an Infection-Free Intraosseus Transcutaneous Amputation ProsthesisR01HD061053 · NICHD · THOMAS JEFFERSON UNIVERSITY · PI ADAMS, CHRISTOPHER S, HICKOK, NOREEN J · 2009 to 2012
$1.3M
A new allograft that promotes long-term, infection-free skeletal repairR01DE019901 · NIDCR · THOMAS JEFFERSON UNIVERSITY · PI ADAMS, CHRISTOPHER S, HICKOK, NOREEN J · 2009 to 2010
$875k
NIA NIH HHS P30 AG024827NICHD NIH HHS R01 HD061053NIDCR NIH HHS R01 DE019901
6 · The paper itself

Abstract

Orthopaedic infections are complex conditions that require immediate diagnosis and accurate identification of the causative organisms to facilitate appropriate management. Conventional methodologies for diagnosis of these infections sometimes lack accuracy or sufficient rapidity. Molecular diagnostics is an emerging area of bench-to-bedside research in orthopaedic infections. Examples of promising molecular diagnostics include measurement of a specific biomarker in the synovial fluid, polymerase chain reaction-based detection of bacterial genes, and metabolomic determination of responses to orthopaedic infection.

Indexed as

BiomarkersBone Diseases, InfectiousDNA, BacterialHumansMetabolomeMolecular Diagnostic TechniquesPolymerase Chain ReactionProsthesis-Related InfectionsSynovial FluidBiomarkersDNA, Bacterial

Identifiers

PMID25808967
PMCPMC4375750
OpenAlexW4244802419

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.