Trial reportPsycho-oncology2016
Reliable change in neuropsychological assessment of breast cancer survivors.
Trial report in Psycho-oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Cognitive functioning in thyroid cancer survivors: a systematic review and meta-analysis.Journal of cancer survivorship : research and practice · 2019Pooled it
- Trial
- Efficacy of Cognitive Training for Treating Cancer-related Cognitive Impairment: Systematic Review and Meta-analysis by Cognitive Domain.Neuropsychology review · 2026Review
- Recent Advances in Neuropsychological Test Interpretation for Clinical Practice.Neuropsychology review · 2024Review
- Assessing objective cognitive impairments in cancer survivors: Features and validity of measures for research and clinical applications.Asia-Pacific journal of oncology nursing · 2023Review
- Neuroimaging based biotypes for precision diagnosis and prognosis in cancer-related cognitive impairment.Frontiers in medicine · 2023Review
- Protocol for the Exercise, Cancer and Cognition - The ECCO-Study: A Randomized Controlled Trial of Simultaneous Exercise During Neo-/Adjuvant Chemotherapy in Breast Cancer Patients and Its Effects on Neurocognition.Frontiers in neurology · 2022Article
- Changes in Attentional Function in Patients From Before Through 12 Months After Breast Cancer Surgery.Journal of pain and symptom management · 2020Article
- Cognitive performance of breast cancer survivors in daily life: Role of fatigue and depressed mood.Psycho-oncology · 2019Article
- Cytokine-associated fatigue prior to, during, and post-chemotherapy for breast cancer.Journal of neuroimmunology · 2019Article
- Relationship of fatigue with cognitive performance in women with early-stage breast cancer over 2 years.Psycho-oncology · 2019Article
- Observational
- Online Self-Administered Cognitive Testing Using the Amsterdam Cognition Scan: Establishing Psychometric Properties and Normative Data.Journal of medical Internet research · 2018Article
- Cognitive Effects of Cancer and Cancer Treatments.Annual review of clinical psychology · 2018Review
- Cognition, quality-of-life, and symptom clusters in breast cancer: Using Bayesian networks to elucidate complex relationships.Psycho-oncology · 2018Article
- Growth of malignant extracranial tumors alters microRNAome in the prefrontal cortex of TumorGraft mice.Oncotarget · 2017Article
- Article
- Minocycline, a putative neuroprotectant, co-administered with doxorubicin-cyclophosphamide chemotherapy in a xenograft model of triple-negative breast cancer.Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie · 2016Article
- The relationship of cognitive performance to concurrent symptoms, cancer- and cancer-treatment-related variables in women with early-stage breast cancer: a 2-year longitudinal study.Journal of cancer research and clinical oncology · 2016Article
- Learning and memory performance in breast cancer survivors 2 to 6 years post-treatment: the role of encoding versus forgetting.Journal of cancer survivorship : research and practice · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundThe purpose of this study was to enhance the current understanding and interpretation of longitudinal change on tests of neurocognitive function in individuals with cancer. Scores on standard neuropsychological instruments may be impacted by practice effects and other random forms of error.
methodsThe current study assessed the test-retest reliability of several tests and overarching cognitive domains comprising a neurocognitive battery typical of those used for research and clinical evaluation using relevant time frames. Practice effect-adjusted reliable change confidence intervals for test-retest difference scores based on a sample of patient-matched healthy controls are provided.
resultsBy applying reliable change confidence intervals to scores from two samples of breast cancer patients at post-treatment follow-up assessment, meaningful levels of detectable change in cognitive functioning in breast cancer survivors were ascertained and indicate that standardized neuropsychological instruments may be subject to limitations in detection of subtle cognitive dysfunction over clinically relevant intervals, especially in patient samples with average to above average range baseline functioning.
conclusionsThese results are discussed in relation to reported prevalence of cognitive change in breast cancer patients along with recommendations for study designs that enhance detection of treatment effects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.