ArticleMolecular biology and evolution2015
A Protocol for Diagnosing the Effect of Calibration Priors on Posterior Time Estimates: A Case Study for the Cambrian Explosion of Animal Phyla.
Article in Molecular biology and evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed.
- The monophyly of Nycteria and Polychromophilus parasites: a missing piece in the evolution of malaria and other Haemosporida.Malaria journal · 2026Article
- A time-calibrated phylogeny of the diversification of Holoadeninae frogs.Frontiers in bioinformatics · 2024Article
- The origin of eukaryotes and rise in complexity were synchronous with the rise in oxygen.Frontiers in bioinformatics · 2023Article
- Assessing the relative performance of fast molecular dating methods for phylogenomic data.BMC genomics · 2022Article
- Large-Scale Phylogenomic Analyses Reveal the Monophyly of Bryophytes and Neoproterozoic Origin of Land Plants.Molecular biology and evolution · 2021Article
- Data-driven speciation tree prior for better species divergence times in calibration-poor molecular phylogenies.Bioinformatics (Oxford, England) · 2021Article
- Molecular dating for phylogenies containing a mix of populations and species by using Bayesian and RelTime approaches.Molecular ecology resources · 2021Article
- Reliable Confidence Intervals for RelTime Estimates of Evolutionary Divergence Times.Molecular biology and evolution · 2020Article
- Theoretical Foundation of the RelTime Method for Estimating Divergence Times from Variable Evolutionary Rates.Molecular biology and evolution · 2018Article
- Global Rate Variation in Bony Vertebrates.Genome biology and evolution · 2018Article
- RelTime Relaxes the Strict Molecular Clock throughout the Phylogeny.Genome biology and evolution · 2018Article
- Mode and Rate of Evolution of Haemosporidian Mitochondrial Genomes: Timing the Radiation of Avian Parasites.Molecular biology and evolution · 2018Article
- Testing the molecular clock using mechanistic models of fossil preservation and molecular evolution.Proceedings. Biological sciences · 2017Article
- Dating early animal evolution using phylogenomic data.Scientific reports · 2017Article
- RelTime Rates Collapse to a Strict Clock When Estimating the Timeline of Animal Diversification.Genome biology and evolution · 2017Article
- Meat and Nicotinamide: A Causal Role in Human Evolution, History, and Demographics.International journal of tryptophan research : IJTR · 2017Review
- The evolution of methods for establishing evolutionary timescales.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- A molecular palaeobiological exploration of arthropod terrestrialization.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Advances in Time Estimation Methods for Molecular Data.Molecular biology and evolution · 2016Article
- Molecular clocks and the early evolution of metazoan nervous systems.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015Review
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5 authors.
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Abstract
We present a procedure to test the effect of calibration priors on estimated times, which applies a recently developed calibration-free approach (RelTime) method that produces relative divergence times for all nodes in the tree. We illustrate this protocol by applying it to a timetree of metazoan diversification (Erwin DH, Laflamme M, Tweedt SM, Sperling EA, Pisani D, Peterson KJ. 2011. The Cambrian conundrum: early divergence and later ecological success in the early history of animals. Science 334:1091-1097.), which placed the divergence of animal phyla close to the time of the Cambrian explosion inferred from the fossil record. These analyses revealed that the two maximum-only calibration priors in the pre-Cambrian are the primary determinants of the young divergence times among animal phyla in this study. In fact, these two maximum-only calibrations produce divergence times that severely violate minimum boundaries of almost all of the other 22 calibration constraints. The use of these 22 calibrations produces dates for metazoan divergences that are hundreds of millions of years earlier in the Proterozoic. Our results encourage the use of calibration-free approaches to identify most influential calibration constraints and to evaluate their impact in order to achieve biologically robust interpretations.
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