ArticleFamily practice2015
Sore throat in primary care project: a clinical score to diagnose viral sore throat.
Article in Family practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Diagnostic models predicting paediatric viral acute respiratory infections: a systematic review.BMJ open · 2023Pooled it
- Comparison of Centor and McIsaac scores in primary care: a meta-analysis over multiple thresholds.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020Pooled it
- Nasopharyngeal carriage of Streptococcus pneumoniae among Brazilian children: Interplay with viral co-infection.PloS one · 2025Article
- Review: Known, Emerging, and Remerging Pharyngitis Pathogens.The Journal of infectious diseases · 2024Review
- Detection of group A streptococcus in children with confirmed viral pharyngitis and antiviral host response.European journal of pediatrics · 2022Observational
- International Delphi-based consensus on the appropriate use and effect of Benzydamine hydrochloride in the treatment of sore throat.BMC primary care · 2022Article
- Diagnostic Accuracy of Centor Score for Diagnosis of Group A Streptococcal Pharyngitis among Adults in Primary Care Clinics in Malaysia.The Malaysian journal of medical sciences : MJMS · 2022Article
- Incidence and clinical features of viral sore throat among children in rural Haryana, India.Journal of family medicine and primary care · 2020Article
- Distribution of Streptococcal Pharyngitis and Acute Rheumatic Fever, Auckland, New Zealand, 2010-2016.Emerging infectious diseases · 2020Article
- Clinical features predicting group A streptococcal pharyngitis in a Japanese paediatric primary emergency medical centre.The Journal of international medical research · 2018Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveViral agents cause the majority of sore throats. However, there is not currently a score to diagnose viral sore throat. The aims of this study were (i) to find the rate of bacterial and viral causes, (ii) to show the seasonal variations and (iii) to form a new scoring system to diagnose viral sore throat.
methodsA throat culture for group A beta haemolytic streptococci (GABHS) and a nasopharyngeal swab to detect 16 respiratory viruses were obtained from each patient. Over a period of 52 weeks, a total of 624 throat cultures and polymerase chain reaction analyses were performed. Logistic regression analysis was performed to find the clinical score.
resultsViral infection was found in 277 patients (44.3%), and GABHS infection was found in 116 patients (18.5%). An infectious cause was found in 356 patients (57.1%). Rhinovirus was the most commonly detected infectious agent overall (highest in November, 34.5%), and the highest GABHS rate was in November (32.7%). Analysis of data provided a scoring system, called the Mistik Score, to diagnose viral sore throat. The predictive model for positive viral analysis included the following variables: absence of headache, stuffy nose, sneezing, temperature of ≥37.5°C on physical examination, and the absence of tonsillar exudate and/or swelling. The probability of a positive viral analysis for a score of 5 was 82.1%.
conclusionThe Mistik Score may be useful to diagnose viral sore throat. We suggest its use either alone or in combination with the Modified Centor Score.
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