ArticleJournal of the Royal Society, Interface2015
Multicomponent model of deformation and detachment of a biofilm under fluid flow.
Article in Journal of the Royal Society, Interface, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Influence of phosphate on bacterial release from activated carbon point-of-use filters and on biofilm characteristics.The Science of the total environment · 2024Article
- Bayesian estimation ofBiofilm · 2023Article
- Anomalous diffusion of nanoparticles in the spatially heterogeneous biofilm environment.iScience · 2023Article
- Combined electromechanically driven pulsating flow of nonlinear viscoelastic fluids in narrow confinements.Journal of the Royal Society, Interface · 2022Article
- Non-invasive Inference of Thrombus Material Properties with Physics-Informed Neural Networks.Computer methods in applied mechanics and engineering · 2021Article
- Effect of Nonphosphorus Corrosion Inhibitors on Biofilm Pore Structure and Mechanical Properties.Environmental science & technology · 2020Article
- Differential Effects of Heated Perfusate on Morphology, Viability, and Dissemination of Staphylococcus epidermidis Biofilms.Applied and environmental microbiology · 2020Article
- A three-dimensional phase-field model for multiscale modeling of thrombus biomechanics in blood vessels.PLoS computational biology · 2020Article
- Article
- Regulating, Measuring, and Modeling the Viscoelasticity of Bacterial BiofilmsJournal of bacteriology · 2019Review
- Article
- Three-phase Model of Visco-elastic Incompressible Fluid Flow and its Computational Implementation.Communications in computational physics · 2019Article
- Continuum and discrete approach in modeling biofilm development and structure: a review.Journal of mathematical biology · 2018Review
- Effects of water flow on submerged macrophyte-biofilm systems in constructed wetlands.Scientific reports · 2018Article
- Effect of divalent ions and a polyphosphate on composition, structure, and stiffness of simulated drinking water biofilms.NPJ biofilms and microbiomes · 2018Article
- Towards standardized mechanical characterization of microbial biofilms: analysis and critical review.NPJ biofilms and microbiomes · 2018Review
- Extracellular Polymeric Matrix Production and Relaxation under Fluid Shear and Mechanical Pressure in Staphylococcus aureus Biofilms.Applied and environmental microbiology · 2018Article
- Model predictions of deformation, embolization and permeability of partially obstructive blood clots under variable shear flow.Journal of the Royal Society, Interface · 2017Article
- Response of Simulated Drinking Water Biofilm Mechanical and Structural Properties to Long-Term Disinfectant Exposure.Environmental science & technology · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
A novel biofilm model is described which systemically couples bacteria, extracellular polymeric substances (EPS) and solvent phases in biofilm. This enables the study of contributions of rheology of individual phases to deformation of biofilm in response to fluid flow as well as interactions between different phases. The model, which is based on first and second laws of thermodynamics, is derived using an energetic variational approach and phase-field method. Phase-field coupling is used to model structural changes of a biofilm. A newly developed unconditionally energy-stable numerical splitting scheme is implemented for computing the numerical solution of the model efficiently. Model simulations predict biofilm cohesive failure for the flow velocity between [Formula: see text] and [Formula: see text] m s(-1) which is consistent with experiments. Simulations predict biofilm deformation resulting in the formation of streamers for EPS exhibiting a viscous-dominated mechanical response and the viscosity of EPS being less than [Formula: see text]. Higher EPS viscosity provides biofilm with greater resistance to deformation and to removal by the flow. Moreover, simulations show that higher EPS elasticity yields the formation of streamers with complex geometries that are more prone to detachment. These model predictions are shown to be in qualitative agreement with experimental observations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.