ArticleJournal of the Royal Society, Interface2015
Periodic traction in migrating large amoeba of Physarum polycephalum.
Article in Journal of the Royal Society, Interface, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 37 citations in OpenAlex.
- Cytoskeletal prestress homeostasis is a biological principle that governs living cell structure and function.Mechanobiology in medicine · 2026Review
- Coexistence of trapped and flow-transported nuclei enables fast pigeon post communication across multinucleated cell.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Tissue-like multicellular development triggered by mechanical compression in archaea.Science (New York, N.Y.) · 2025Article
- Dynamics of centipede locomotion revealed by large-scale traction force microscopy.Journal of the Royal Society, Interface · 2024Article
- Go with the flow - bulk transport by molecular motors.Journal of cell science · 2023Review
- Tracking Mechanical Stress and Cell Migration with Inexpensive Polymer Thin-Film Sensors.Advanced materials interfaces · 2023Article
- Random walk and cell morphology dynamics inFrontiers in cell and developmental biology · 2023Article
- Giant cells: multiple cells unite to survive.Frontiers in cellular and infection microbiology · 2023Review
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- Encoding memory in tube diameter hierarchy of living flow network.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
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- Oscillatory fluid flow drives scaling of contraction wave with system size.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Fluid flows shaping organism morphology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Review
- Self-organized mechano-chemical dynamics in amoeboid locomotion ofJournal of physics D: Applied physics · 2017Article
- Mechanism of signal propagation inProceedings of the National Academy of Sciences of the United States of America · 2017Article
- Coordination of contractility, adhesion and flow in migrating Physarum amoebae.Journal of the Royal Society, Interface · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The slime mould Physarum polycephalum is a giant multinucleated cell exhibiting well-known Ca(2+)-dependent actomyosin contractions of its vein network driving the so-called cytoplasmic shuttle streaming. Its actomyosin network forms both a filamentous cortical layer and large fibrils. In order to understand the role of each structure in the locomotory activity, we performed birefringence observations and traction force microscopy on excised fragments of Physarum. After several hours, these microplasmodia adopt three main morphologies: flat motile amoeba, chain types with round contractile heads connected by tubes and motile hybrid types. Each type exhibits oscillations with a period of about 1.5 min of cell area, traction forces and fibril activity (retardance) when fibrils are present. The amoeboid types show only peripheral forces while the chain types present a never-reported force pattern with contractile rings far from the cell boundary under the spherical heads. Forces are mostly transmitted where the actomyosin cortical layer anchors to the substratum, but fibrils maintain highly invaginated structures and contribute to forces by increasing the length of the anchorage line. Microplasmodia are motile only when there is an asymmetry in the shape and/or the force distribution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.