ReviewInternational journal of molecular sciences2015
Coronary artery calcium screening: does it perform better than other cardiovascular risk stratification tools?
Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- HDL-cholesterol concentration and its association with coronary artery calcification: a systematic review and meta-analysis.Lipids in health and disease · 2023Pooled it
- Diabetes and Hypertension Consistently Predict the Presence and Extent of Coronary Artery Calcification in Symptomatic Patients: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2016Pooled it
- Opportunistic Cardiovascular Risk Assessment in the Eye Clinic: Validation of a Retinal Deep Learning-Based 10-Year Atherosclerotic Cardiovascular Disease Estimator.Ophthalmology science · 2026Article
- Addition of CAD polygenic risk score to coronary artery calcium score enhances prediction of MACE.Frontiers in cardiovascular medicine · 2026Article
- Beyond Traditional Risk Calculators: The Expanding Role of Coronary Artery Calcium Scoring in Preventive Cardiology.Cureus · 2025Review
- Associations between per- and polyfluoroalkyl chemicals and abdominal aortic calcification in middle-aged and older adults.Journal of advanced research · 2025Article
- Carotid atherosclerotic plaque microcalcification is independently associated with recurrent neurovascular events: A pilot study.International journal of stroke : official journal of the International Stroke Society · 2024Article
- Incidental Coronary Artery Calcification and the Risk of Major Adverse Cardiovascular Outcomes.Cureus · 2024Article
- Will DANCAVAS be the most important screening trial in the last 50 years?American journal of preventive cardiology · 2024Article
- Association between systemic immune-inflammation index and psoriasis: a population-based study.Frontiers in immunology · 2024Article
- Coronary artery calcification as a predictor of adverse outcomes in patients hospitalized with COVID-19.American heart journal plus : cardiology research and practice · 2023Article
- Radiation Doses in Patients Undergoing Computed Tomographic Coronary Artery Calcium Evaluation With a 64-Slice Scanner Versus a 256-Slice Scanner.Texas Heart Institute journal · 2022Article
- Prevalence of Atherosclerosis in Psoriatic Patients Detected with Epiaortic Color Doppler Ultrasound and Computed Tomography Angiography.Dermatology practical & conceptual · 2022Article
- Association of Trabecular Bone Score-Adjusted Fracture Risk Assessment Tool with Coronary Artery Calcification in Women.Diagnostics (Basel, Switzerland) · 2022Article
- Per- and polyfluoroalkyl substances and calcifications of the coronary and aortic arteries in adults with prediabetes: Results from the diabetes prevention program outcomes study.Environment international · 2021Article
- HDL-C and non-HDL-C levels are associated with anthropometric and biochemical parameters.Jornal vascular brasileiro · 2019Article
- Psoriasis and Cardiovascular Comorbidities: Focusing on Severe Vascular Events, Cardiovascular Risk Factors and Implications for Treatment.International journal of molecular sciences · 2017Review
- Fatty Liver, Insulin Resistance, and Obesity: Relationships With Increase in Coronary Artery Calcium Over Time.Clinical cardiology · 2016Article
- ESC 2019 guidelines on chronic coronary syndromes: could calcium scoring improve detection of coronary artery disease in patients with low risk score. Findings from a retrospective cohort of patients in a district general hospital.JRSM cardiovascular diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronary artery calcium (CAC) has been advocated as one of the strongest cardiovascular risk prediction markers. It performs better across a wide range of Framingham risk categories (6%-10% and 10%-20% 10-year risk categories) and also helps in reclassifying the risk of these subjects into either higher or lower risk categories based on CAC scores. It also performs better among population subgroups where Framingham risk score does not perform well, especially young subjects, women, family history of premature coronary artery disease and ethnic differences in coronary risk. The absence of CAC is also associated with excellent prognosis, with 10-year event rate of 1%. Studies have also compared with other commonly used markers of cardiovascular disease risk such as Carotid intima-media thickness and highly sensitive C-reactive protein. CAC also performs better compared with carotid intima-media thickness and highly sensitive C-reactive protein in prediction of coronary heart disease and cardiovascular disease events. CAC scans are associated with relatively low radiation exposure (0.9-1.1 mSv) and provide information that can be used not only for risk stratification but also can be used to track the progression of atherosclerosis and the effects of statins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.