ArticleNature communications2015
A novel pathway producing dimethylsulphide in bacteria is widespread in soil environments.
Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
48 citing papers in PubMed, 109 citations in OpenAlex.
- Function, Structure, and Regulation of Nitrogen Fixation-like Metalloproteins for Nitrogen, Energy, Carbon, and Sulfur Metabolism.Chemical reviews · 2026Review
- Metagenomic insights into the taxonomic and metabolic diversity of the microbiome of Lake Karum in the Danakil Depression, Ethiopia.Environmental microbiome · 2026Article
- Review
- Dimethylsulfoniopropionate metabolism shapes microbial ecology and physiological adaptation during the austral winter in Southern Ocean sea ice and seawater.Nature communications · 2026Article
- Abiotic Methane Production Driven by Soil Reactive Oxygen Species.Environmental science & technology · 2026Article
- Gap Analysis of Metabolic Conversions of Off-Flavors and Antinutrients in Plant-Based Substrates.Comprehensive reviews in food science and food safety · 2026Review
- Two Novel S-methyltransferases Confer Dimethylsulfide Production in Actinomycetota.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Predicted shifts in bacterial and algal contributions to DMSP and DMS dynamics during a coastal spring-summer bloom.The ISME journal · 2026Article
- Elucidation of dimethyl sulfide assimilation in soil bacteria expands the enzymatic landscape of terrestrial sulfur cycling.The ISME journal · 2026Article
- Ecological Diversity, Metabolic Versatility, and Biotechnological Applications ofAntibiotics (Basel, Switzerland) · 2025Review
- An S-methyltransferase that produces the climate-active gas dimethylsulfide is widespread across diverse marine bacteria.Nature microbiology · 2024Article
- High-quality identification of volatile organic compounds (VOCs) originating from breath.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Understanding Biomineralization Mechanisms to Produce Size-Controlled, Tailored Nanocrystals for Optoelectronic and Catalytic Applications: A Review.ACS applied nano materials · 2024Review
- Article
- Alternative dimethylsulfoniopropionate biosynthesis enzymes in diverse and abundant microorganisms.Nature microbiology · 2024Article
- Methanolobus use unspecific methyltransferases to produce methane from dimethylsulphide in Baltic Sea sediments.Microbiome · 2024Article
- Quorum Sensing Regulates the Production of Methanethiol inMicroorganisms · 2023Article
- DMSOP-cleaving enzymes are diverse and widely distributed in marine microorganisms.Nature microbiology · 2023Article
- Aerobic methylation of hydrogen sulfide to dimethylsulfide in diverse microorganisms and environments.The ISME journal · 2023Article
- Microbial Dimethylsulfoniopropionate Cycling in Deep Sediment of the Mariana Trench.Applied and environmental microbiology · 2023Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The volatile compound dimethylsulphide (DMS) is important in climate regulation, the sulphur cycle and signalling to higher organisms. Microbial catabolism of the marine osmolyte dimethylsulphoniopropionate (DMSP) is thought to be the major biological process generating DMS. Here we report the discovery and characterization of the first gene for DMSP-independent DMS production in any bacterium. This gene, mddA, encodes a methyltransferase that methylates methanethiol and generates DMS. MddA functions in many taxonomically diverse bacteria including sediment-dwelling pseudomonads, nitrogen-fixing bradyrhizobia and cyanobacteria, and mycobacteria including the pathogen Mycobacterium tuberculosis. The mddA gene is present in metagenomes from varied environments, being particularly abundant in soil environments, where it is predicted to occur in up to 76% of bacteria. This novel pathway may significantly contribute to global DMS emissions, especially in terrestrial environments and could represent a shift from the notion that DMSP is the only significant precursor of DMS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.