Evidence map›Paper›PMID 25807224›Full record

ReviewCurrent opinion in cardiology2015

Diagnosing and treating the failing right heart.

John J Ryan, Ryan J Tedford

Abstract readReview
In one paragraph

Review in Current opinion in cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. CD34Stem cells translational medicine · 2018
    Trial
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John J RyanaDivision of Cardiovascular Medicine, Department of Medicine, University of Utah, Salt Lake City, Utah bDivision of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland USA.
Ryan J Tedford

Funding

Mechanisms of Right Ventricular Dysfunction in Scleroderma-associated PAHR01HL114910 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI HASSOUN, PAUL M. · 2012 to 2023
$6.2M
NCATS NIH HHS L30 TR001034NHLBI NIH HHS 1R01HL114910-03NHLBI NIH HHS L30 HL110304NHLBI NIH HHS R01 HL114910
6 · The paper itself

Abstract

purpose of reviewRight ventricular failure (RVF) is associated with significant morbidity and mortality. There is an increasing interest in proper assessment of right ventricle (RV) function as well as understanding mechanisms behind RVF. RECENT

findingsWithin this article, we discuss the metabolic changes that occur in the RV in response to RVF, in particular, a shift toward glycolysis and increased glutaminolysis. We will detail the advances made in noninvasive imaging in assessing the function of the RV and review the methods to assess right ventricle-pulmonary artery coupling. We lastly investigate the role of new treatment options in the failing RV, such as β-blocker therapy. SUMMARY: RVF is a complicated entity. Although some inferences on RV function and treatment can be made from our understanding of the left ventricle, the RV has unique features, anatomically, metabolically and embryologically, that require dedicated RV-directed research.

Indexed as

Adrenergic beta-AntagonistsCardiac CatheterizationEchocardiographyGlucoseGlutamineGlycolysisHeart FailureHeart VentriclesHumansMagnetic Resonance ImagingPulmonary ArteryVentricular Dysfunction, RightAdrenergic beta-AntagonistsGlucoseGlutamine

Identifiers

PMID25807224
PMCPMC4429511

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.