Evidence map›Paper›PMID 25807209›Full record

ArticlePlant signaling & behavior2015

Rice ubiquitin ligase EL5 prevents root meristematic cell death under high nitrogen conditions and interacts with a cytosolic GAPDH.

Yoko Nishizawa, Susumu Mochizuki, Hanae Koiwai, Katsuhiko Kondo, Kyutaro Kishimoto, Etsuko Katoh, Eiichi Minami

Open access · bronzeAbstract read
In one paragraph

Article in Plant signaling & behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. A Knockout of theGenes · 2025
    Article
  3. TheFrontiers in plant science · 2024
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yoko Nishizawaa National Institute of Agrobiological Sciences ; Tsukuba , Japan.
Susumu Mochizuki
Hanae Koiwai
Katsuhiko Kondo
Kyutaro Kishimoto
Etsuko Katoh
Eiichi Minami
Institute of Agrobiological Sciences · JPInstitute of Vegetable and Floriculture Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Root formation in rice transformants overexpressing mutated EL5 (mEL5) was severely inhibited because of meristematic cell death. Cell death was caused by nitrogen sources, particularly nitrate forms, in the culture medium. Nitrite treatment increased the cytokinin contents in roots, but mEL5 contained more cytokinins than non-transformants. Transcriptome profiling showed overlaps between nitrite-responsive genes in non-transformants and genes with altered expression in untreated mEL5. These results indicate that impairment of EL5 function activates nitrogen signaling despite the absence of a nitrogen source. Physical interaction between the EL5 C-terminal region and a cytosolic glyceraldehyde-3-phosphate dehydrogenase, OsGapC2, was demonstrated in vitro and in vivo. Elucidation of the role of glyceraldehyde-3-phosphate dehydrogenase in oxidative cell death in plants is expected in future.

Indexed as

Cell DeathCytokininsCytosolGene ExpressionGenes, PlantGlyceraldehyde-3-Phosphate DehydrogenasesLigasesMeristemNitritesNitrogenOryzaPlant CellsPlant ProteinsPlant RootsSignal TransductionUbiquitinCytokininsGlyceraldehyde-3-Phosphate DehydrogenasesLigasesNitritesNitrogenPlant ProteinsUbiquitinUbiquitin-Protein LigasescytokininGAPDHnitrogenreactive oxygen speciesriceroot cell deathubiquitin ligase

Identifiers

PMID25807209
PMCPMC4623351
OpenAlexW2045923885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.