ArticlePloS one2015
Chronic stress induces a hyporeactivity of the autonomic nervous system in response to acute mental stressor and impairs cognitive performance in business executives.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 72 citations in OpenAlex.
- Estradiol Therapy After Menopause Mitigates Effects of Stress on Cortisol and Working Memory.The Journal of clinical endocrinology and metabolism · 2017Trial
- Stress and salivary cortisol in emergency medical dispatchers: A randomized shifts control trial.PloS one · 2017Trial
- Self-Reported Red Eye Among Saudi Adults: Symptom Profile, Self-Management Practices, and Associated Factors.Healthcare (Basel, Switzerland) · 2026Article
- Reduced Complexity of Pulse Rate Is Associated With Faster Cognitive Decline in Older Adults.Journal of the American Heart Association · 2025Article
- Cardiovascular Disease Risk Factors in the Native American Population.Journal of cardiovascular development and disease · 2025Review
- Why mindfulness matters in musculoskeletal therapies: a narrative review.Frontiers in psychology · 2025Review
- Advancing the allostatic load model in military training research: from theory to application.Frontiers in physiology · 2025Review
- The effect of heart rate variability on the choroidal vascularity of the optical coherence tomography and angiography in central serous chorioretinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Genetic and environmental influences on alpha amylase stress reactivity and shared genetic covariation with cortisol.Psychoneuroendocrinology · 2024Article
- Stress, Inflammation and Metabolic Biomarkers Are Associated with Body Composition Measures in Lean, Overweight, and Obese Children and Adolescents.Children (Basel, Switzerland) · 2022Article
- Strategies to Limit Cognitive Impairments under Sleep Restriction: Relationship to Stress Biomarkers.Brain sciences · 2022Article
- Immunosensor Based on Zinc Oxide Nanocrystals Decorated with Copper for the Electrochemical Detection of Human Salivary Alpha-Amylase.Micromachines · 2021Article
- Stress Enhances Proinflammatory Platelet Activity: the Impact of Acute and Chronic Mental Stress.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021Article
- Association of salivary alpha-amylase with anxiety and stress in nursing professionals.Revista latino-americana de enfermagem · 2021Article
- Article
- Cortisol Awakening Response, Self-Reported Affect and Exam Performance in Female Students.Applied psychophysiology and biofeedback · 2020Article
- Minimally-invasive methods for examining biological changes in response to chronic stress: A scoping review.International journal of nursing studies · 2020Article
- Frozen by stress: Stress increases scope insensitivity.PloS one · 2019Article
- Pubertal Hormonal Changes and the Autonomic Nervous System: Potential Role in Pediatric Orthostatic Intolerance.Frontiers in neuroscience · 2019Review
- Objective detection of chronic stress using physiological parameters.Medical & biological engineering & computing · 2018Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study examined the incidence of chronic stress in business executives (109 subjects: 75 male and 34 female) and its relationship with cortisol levels, cognitive performance, and autonomic nervous system (ANS) reactivity after an acute mental stressor. Blood samples were collected from the subjects to measure cortisol concentration. After the sample collection, the subjects completed the Lipp Inventory of Stress Symptoms for Adults and the Stroop Color-Word Test to evaluate stress and cognitive performance levels, respectively. Saliva samples were collected prior to, immediately after, and five minutes after the test. The results revealed that 90.1% of the stressed subjects experienced stress phases that are considered chronic stress. At rest, the subjects with chronic stress showed higher cortisol levels, and no gender differences were observed. No differences were found between the stressed and non-stressed subjects regarding salivary amylase activity prior to test. Chronic stress also impaired performance on the Stroop test, which revealed higher rates of error and longer reaction times in the incongruent stimulus task independently of gender. For the congruent stimulus task of the Stroop test, the stressed males presented a higher rate of errors than the non-stressed males and a longer reaction time than the stressed females. After the acute mental stressor, the non-stressed male group showed an increase in salivary alpha-amylase activity, which returned to the initial values five minutes after the test; this ANS reactivity was not observed in the chronically stressed male subjects. The ANS responses of the non-stressed vs stressed female groups were not different prior to or after the Stroop test. This study is the first to demonstrate a blunted reactivity of the ANS when male subjects with chronic psychological stress were subjected to an acute mental stressor, and this change could contribute to impairments in cognitive performance.
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