ArticlePloS one2015
Genetic and molecular characterization of submergence response identifies Subtol6 as a major submergence tolerance locus in maize.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 81 citations in OpenAlex.
- Flooding-induced transcriptomic responses and yield stability in oil palm (Elaeis guineensis).Planta · 2026Article
- Transcriptome analysis of fenugreek under mixed saline-alkali stress.Frontiers in plant science · 2026Article
- Stress-responsive transcription factor families are key components of the core abiotic stress response in maize.G3 (Bethesda, Md.) · 2025Article
- Decoding plant responses to waterlogging: from stress signals to molecular mechanisms and their future implications.Plant molecular biology · 2025Review
- Identification and core gene-mining of Weighted Gene Co-expression Network Analysis-based co-expression modules related to flood resistance in quinoa seedlings.BMC genomics · 2024Article
- Differential leaf flooding resilience in Arabidopsis thaliana is controlled by ethylene signaling-activated and age-dependent phosphorylation of ORESARA1.Plant communications · 2024Article
- Plant Adaptation to Flooding Stress under Changing Climate Conditions: Ongoing Breakthroughs and Future Challenges.Plants (Basel, Switzerland) · 2023Review
- Submergence Stress Alters the Expression of Clock Genes and Configures New Zeniths and Expression of Outputs inInternational journal of molecular sciences · 2023Article
- Exploring the Potential of Multiomics and Other Integrative Approaches for Improving Waterlogging Tolerance in Plants.Plants (Basel, Switzerland) · 2023Review
- Plant responses to limited aeration: Advances and future challenges.Plant direct · 2023Article
- QTL and Candidate Genes: Techniques and Advancement in Abiotic Stress Resistance Breeding of Major Cereals.International journal of molecular sciences · 2022Review
- Identification of Functional Genetic Variations Underlying Flooding Tolerance in Brazilian Soybean Genotypes.International journal of molecular sciences · 2022Article
- Water stress resilient cereal crops: Lessons from wild relatives.Journal of integrative plant biology · 2022Review
- Genome-wide association study reveals quantitative trait loci for waterlogging-triggered adventitious roots and aerenchyma formation in common wheat.Frontiers in plant science · 2022Article
- Transcriptomic profiling suggests candidate molecular responses to waterlogging in cassava.PloS one · 2022Article
- Opportunities for Improving Waterlogging Tolerance in Cereal Crops-Physiological Traits and Genetic Mechanisms.Plants (Basel, Switzerland) · 2021Review
- Phospholipases C and D and Their Role in Biotic and Abiotic Stresses.Plants (Basel, Switzerland) · 2021Review
- Sugar modulation of anaerobic-response networks in maize root tips.Plant physiology · 2021Article
- Plant Morphological, Physiological and Anatomical Adaption to Flooding Stress and the Underlying Molecular Mechanisms.International journal of molecular sciences · 2021Review
- Secretome Analysis ofProteomes · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maize is highly sensitive to short term flooding and submergence. Early season flooding reduces germination, survival and growth rate of maize seedlings. We aimed to discover genetic variation for submergence tolerance in maize and elucidate the genetic basis of submergence tolerance through transcriptional profiling and linkage analysis of contrasting genotypes. A diverse set of maize nested association mapping (NAM) founder lines were screened, and two highly tolerant (Mo18W and M162W) and sensitive (B97 and B73) genotypes were identified. Tolerant lines exhibited delayed senescence and lower oxidative stress levels compared to sensitive lines. Transcriptome analysis was performed on these inbreds to provide genome level insights into the molecular responses to submergence. Tolerant lines had higher transcript abundance of several fermentation-related genes and an unannotated Pyrophosphate-Dependent Fructose-6-Phosphate 1-Phosphotransferase gene during submergence. A coexpression network enriched for CBF (C-REPEAT/DRE BINDING FACTOR: C-REPEAT/DRE BINDING FACTOR) genes, was induced by submergence in all four inbreds, but was more activated in the tolerant Mo18W. A recombinant inbred line (RIL) population derived from Mo18W and B73 was screened for submergence tolerance. A major QTL named Subtol6 was mapped to chromosome 6 that explains 22% of the phenotypic variation within the RIL population. We identified two candidate genes (HEMOGLOBIN2 and RAV1) underlying Subtol6 based on contrasting expression patterns observed in B73 and Mo18W. Sources of tolerance identified in this study (Subtol6) can be useful to increase survival rate during flooding events that are predicted to increase in frequency with climate change.
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