ReviewFrontiers in bioengineering and biotechnology2015
Can the natural diversity of quorum-sensing advance synthetic biology?
Review in Frontiers in bioengineering and biotechnology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Engineering N-acyl-homoserine lactone-based quorum-sensing circuit for dynamic regulatory control in Saccharomyces cerevisiae.Communications biology · 2025Article
- Synthetic Homoserine Lactone Sensors for Gram-PositiveACS synthetic biology · 2024Article
- Addressable and adaptable intercellular communication via DNA messaging.Nature communications · 2023Article
- Article
- Engineering controllable biofilms for biotechnological applications.Microbial biotechnology · 2021Article
- Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria.Nature microbiology · 2020Article
- Regulating, Measuring, and Modeling the Viscoelasticity of Bacterial BiofilmsJournal of bacteriology · 2019Review
- Article
- Synthetic Switches and Regulatory Circuits in Plants.Plant physiology · 2019Review
- Engineered Orthogonal Quorum Sensing Systems for Synthetic Gene Regulation inFrontiers in bioengineering and biotechnology · 2019Article
- Metabolite-based mutualism enhances hydrogen production in a two-species microbial consortium.Communications biology · 2019Article
- A scalable peptide-GPCR language for engineering multicellular communication.Nature communications · 2018Article
- New approaches in bioprocess-control: Consortium guidance by synthetic cell-cell communication based on fungal pheromones.Engineering in life sciences · 2018Review
- Programmed hierarchical patterning of bacterial populations.Nature communications · 2018Article
- Article
- Quantifying the strength of quorum sensing crosstalk within microbial communities.PLoS computational biology · 2017Article
- Microscopic agents programmed by DNA circuits.Nature nanotechnology · 2017Article
- Insightful directed evolution of Escherichia coli quorum sensing promoter region of the lsrACDBFG operon: a tool for synthetic biology systems and protein expression.Nucleic acids research · 2016Article
- Quorum Sensing Communication Modules for Microbial Consortia.ACS synthetic biology · 2016Article
- The cellular Ising model: a framework for phase transitions in multicellular environments.Journal of the Royal Society, Interface · 2016Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quorum-sensing networks enable bacteria to sense and respond to chemical signals produced by neighboring bacteria. They are widespread: over 100 morphologically and genetically distinct species of eubacteria are known to use quorum sensing to control gene expression. This diversity suggests the potential to use natural protein variants to engineer parallel, input-specific, cell-cell communication pathways. However, only three distinct signaling pathways, Lux, Las, and Rhl, have been adapted for and broadly used in engineered systems. The paucity of unique quorum-sensing systems and their propensity for crosstalk limits the usefulness of our current quorum-sensing toolkit. This review discusses the need for more signaling pathways, roadblocks to using multiple pathways in parallel, and strategies for expanding the quorum-sensing toolbox for synthetic biology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.