Evidence map›Paper›PMID 25806002›Full record

ArticleFrontiers in physiology2015

Complexity analyses show two distinct types of nonlinear dynamics in short heart period variability recordings.

Alberto Porta, Vlasta Bari, Andrea Marchi, Beatrice De Maria, Dirk Cysarz, Peter Van Leeuwen, Anielle C M Takahashi, Aparecida M Catai, Tomaso Gnecchi-Ruscone

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02990793 (A Prospective, Double Blind, Randomized, Sham-Controlled, Clinical Trial to Evaluate The Safety And Efficacy Of Biometrics-Guided Magnetic EEG Resonance Therapy), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02990793 nacompletednot on this mapstarted 2022, after this paper: background citation

A Prospective, Double Blind, Randomized, Sham-Controlled, Clinical Trial to Evaluate The Safety And Efficacy Of Biometrics-Guided Magnetic EEG Resonance Therapy (MeRT) Treatment Of Post-Traumatic Stress Disorder

TypeinterventionalSponsorWave NeuroscienceRan2022 to 2025Enrolled158ConditionsPostTraumatic Stress Disorder, Traumatic Brain Injury, Postconcussive SymptomsArmsActive MeRT Treatment, Sham MeRT Treatment
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 3 countries.

Alberto PortaLaboratory of Complex System Modeling, Department of Biomedical Sciences for Health, University of Milan Milan, Italy ; IRCCS Galeazzi Orthopedic Institute Milan, Italy.
Vlasta BariDepartment of Cardiothoracic, Vascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato Milan, Italy.
Andrea MarchiDepartment of Anesthesia and Intensive Care Unit, Humanitas Clinical and Research Center Rozzano, Italy.
Beatrice De MariaIRCCS Fondazione Salvatore Maugeri Milan, Italy.
Dirk CysarzIntegrated Curriculum for Anthroposophic Medicine, University of Witten/Herdecke Witten, Germany ; Department of Medicine, Institute for Integrative Medicine, University of Witten/Herdecke Herdecke, Germany.
Peter Van LeeuwenDepartment of Biomagnetism, Grönemeyer Institute for Microtherapy, University of Witten/Herdecke Bochum, Germany.
Anielle C M TakahashiResearch Laboratory in Health Elderly, Department of Physiotherapy, Federal University of São Carlos São Carlos, Brazil ; Cardiovascular Physiotherapy Laboratory, Department of Physiotherapy, Nucleus of Research in Physical Exercise, Federal University of São Carlos São Carlos, Brazil.
Aparecida M CataiCardiovascular Physiotherapy Laboratory, Department of Physiotherapy, Nucleus of Research in Physical Exercise, Federal University of São Carlos São Carlos, Brazil.
Tomaso Gnecchi-RusconeDepartment of Cardiology, S.L. Mandic Hospital Merate, Italy.
Universidade Federal de São Carlos · BRFondazione Salvatore Maugeri · ITGrönemeyer Institute for MicroTherapy · DEHumanitas University · ITIRCCS Policlinico San Donato · ITUniversity of Milan · ITWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two diverse complexity metrics quantifying time irreversibility and local prediction, in connection with a surrogate data approach, were utilized to detect nonlinear dynamics in short heart period (HP) variability series recorded in fetuses, as a function of the gestational period, and in healthy humans, as a function of the magnitude of the orthostatic challenge. The metrics indicated the presence of two distinct types of nonlinear HP dynamics characterized by diverse ranges of time scales. These findings stress the need to render more specific the analysis of nonlinear components of HP dynamics by accounting for different temporal scales.

Indexed as

autonomic nervous systemcardiovascular controlgestational agehead-up tiltheart rate variabilitylocal predictionmultiscale analysistime irreversibility

Identifiers

PMID25806002
PMCPMC4354335
OpenAlexW2094207617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.