ReviewFrontiers in human neuroscience2015
Across the consciousness continuum-from unresponsive wakefulness to sleep.
Review in Frontiers in human neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Inter-individual variability in neural response to low doses of LSD.Translational psychiatry · 2024Trial
- Detecting EEG index of arousal in sleeping patients with unresponsive wakefulness syndrome.iScience · 2026Article
- Advancing EEG-based assessment of consciousness and cognition in prolonged disorders of consciousness.Communications medicine · 2026Article
- Phase-dependent stimulation response is shaped by the brain's dynamic functional connectivity.Network neuroscience (Cambridge, Mass.) · 2026Article
- Modulating satiety with neuro-music: a frequency-specific acoustic approach to appetite control.Frontiers in human neuroscience · 2026Article
- Perspectives, attitudes and experiences of introducing noninvasive medical technologies in end-of-life care: a scoping review.BMC palliative care · 2025Article
- Identifying Features of Electroencephalography Associated with Improved Awareness in Persistent Vegetative State via Multiscale Entropy: A Machine Learning Modeling Study.Neurotrauma reports · 2025Article
- Classifying Unconscious, Psychedelic, and Neuropsychiatric Brain States with Functional Connectivity, Graph Theory, and Cortical Gradient Analysis.Brain sciences · 2024Article
- The Constrained Disorder Principle May Account for Consciousness.Brain sciences · 2024Review
- Sleep in Disorders of Consciousness: A Brief Overview on a Still under Investigated Issue.Brain sciences · 2023Review
- Genetics of circadian rhythms and sleep in human health and disease.Nature reviews. Genetics · 2023Review
- A scoping review for building a criticality-based conceptual framework of altered states of consciousness.Frontiers in systems neuroscience · 2023Article
- Validity of the Early Functional Ability scale (EFA) among critically ill patients undergoing early neurological rehabilitation.BMC neurology · 2022Article
- Sleep Treatments in Disorders of Consciousness: A Systematic Review.Diagnostics (Basel, Switzerland) · 2021Review
- Sleep Disorders in Children With Autism Spectrum Disorder: Insights From Animal Models, Especially Non-human Primate Model.Frontiers in behavioral neuroscience · 2021Review
- Identifying Criteria for the Evaluation of the Implications of Brain Reading for Mental Privacy.Science and engineering ethics · 2019Article
- Sleep in patients with disorders of consciousness characterized by means of machine learning.PloS one · 2018Article
- Significance of circadian rhythms in severely brain-injured patients: A clue to consciousness?Neurology · 2017Article
- Article
- Sleep/Wake Modulation of Polysomnographic Patterns has Prognostic Value in Pediatric Unresponsive Wakefulness Syndrome.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Advances in the development of new paradigms as well as in neuroimaging techniques nowadays enable us to make inferences about the level of consciousness patients with disorders of consciousness (DOC) retain. They, moreover, allow to predict their probable development. Today, we know that certain brain responses (e.g., event-related potentials or oscillatory changes) to stimulation, circadian rhythmicity, the presence or absence of sleep patterns as well as measures of resting state brain activity can serve the diagnostic and prognostic evaluation process. Still, the paradigms we are using nowadays do not allow to disentangle VS/UWS and minimally conscious state (MCS) patients with the desired reliability and validity. Furthermore, even rather well-established methods have, unfortunately, not found their way into clinical routine yet. We here review current literature as well as recent findings from our group and discuss how neuroimaging methods (fMRI, PET) and particularly electroencephalography (EEG) can be used to investigate cognition in DOC or even to assess the degree of residual awareness. We, moreover, propose that circadian rhythmicity and sleep in brain-injured patients are promising fields of research in this context.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.