Evidence map›Paper›PMID 25805956›Full record

ArticleWorld journal of gastroenterology2015

Rare case of Helicobacter pylori-positive multiorgan IgG4-related disease and gastric cancer.

Min Li, Qiang Zhou, Kun Yang, David R Brigstock, Lu Zhang, Ming Xiu, Li Sun, Run-Ping Gao

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Min LiMin Li, Qiang Zhou, Kun Yang, Lu Zhang, Ming Xiu, Li Sun, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Qiang ZhouMin Li, Qiang Zhou, Kun Yang, Lu Zhang, Ming Xiu, Li Sun, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Kun YangMin Li, Qiang Zhou, Kun Yang, Lu Zhang, Ming Xiu, Li Sun, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
David R BrigstockMin Li, Qiang Zhou, Kun Yang, Lu Zhang, Ming Xiu, Li Sun, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Lu ZhangMin Li, Qiang Zhou, Kun Yang, Lu Zhang, Ming Xiu, Li Sun, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Ming XiuMin Li, Qiang Zhou, Kun Yang, Lu Zhang, Ming Xiu, Li Sun, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Li SunMin Li, Qiang Zhou, Kun Yang, Lu Zhang, Ming Xiu, Li Sun, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Run-Ping GaoMin Li, Qiang Zhou, Kun Yang, Lu Zhang, Ming Xiu, Li Sun, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 61-year-old male from Northeast China presented with a 2-mo history of abdominal distension, pruritus and jaundice. Laboratory testing revealed an elevated serum IgG4 level. A computed tomography scan showed a typical feature of autoimmune pancreatitis (AIP) and cholecystocholangitis. Early gastric cancer was incidentally discovered when endoscopic untrasound-guided fine needle aspiration (EUS-FNA) of the pancreas was carried out. The patient underwent radical subtotal gastrectomy for gastric cancer combined with cholecystectomy. Helicobacter pylori (H. pylori) and IgG4-positive plasmacytes were detected in gastric cancer tissue, pancreatic EUS-FNA sample and resected gallbladder specimen by immunohistochemistry. The patient was diagnosed with H. pylori-positive IgG4-related AIP and sclerosing cholecystocholangitis as well as H. pylori-positive gastric cancer. He responded well to steroid therapy and remains healthy with no signs of recurrence at one year follow-up. We speculate that H. pylori might act as a trigger via direct or indirect action in the initiation of onset of gastric cancer and multiorgan IgG4-related disease.

Indexed as

Adrenal Cortex HormonesAnti-Bacterial AgentsAutoimmune DiseasesBiomarkersBiopsyCholangitis, SclerosingCholecystectomyGastrectomyHelicobacter InfectionsHelicobacter pyloriHumansImmunoglobulin GIncidental FindingsMaleMiddle AgedPancreatitisAdrenal Cortex HormonesAnti-Bacterial AgentsBiomarkersImmunoglobulin GProton Pump InhibitorsGastric cancerHelicobacter pyloriIgG4-related diseaseSclerosing cholecystocholangitisType 1 autoimmune pancreatitis

Identifiers

PMID25805956
PMCPMC4363779
OpenAlexW263257960

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.