Evidence map›Paper›PMID 25805849›Full record

ArticleGenetics2015

A novel approach for studying histone H1 function in vivo.

Giorgia Siriaco, Renate Deuring, Gina D Mawla, John W Tamkun

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Giorgia SiriacoDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064.
Renate DeuringDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064.
Gina D MawlaDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064.
John W TamkunDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064 tamkun@ucsc.edu.
University of California, Santa Cruz · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Studies of Chromatin Remodeling FactorsR01GM049883 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI TAMKUN, JOHN W. · 1993 to 2013
$3.9M
NIGMS NIH HHS GM49883NIGMS NIH HHS R01 GM049883NIH HHS P40 OD018537
6 · The paper itself

Abstract

In this report, we investigate the mechanisms that regulate Drosophila histone H1 expression and its association with chromatin in vivo. We show that histone H1 is subject to negative autoregulation and exploit this result to examine the effects of mutations of the main phosphorylation site of histone H1.

Indexed as

AnimalsChromatinDrosophilaDrosophila ProteinsGreen Fluorescent ProteinsHistonesMicroscopy, FluorescenceChromatinDrosophila ProteinsGreen Fluorescent ProteinsHistoneschromatinDrosophilagene expressionhistone H1

Identifiers

PMID25805849
PMCPMC4423370
OpenAlexW2006040907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.