SynthesisBMJ open2015
Laparoscopic assistance for primary transanal pull-through in Hirschsprung's disease: a systematic review and meta-analysis.
Synthesis in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Does laparoscopic-assisted transanal endorectal pull-through improve outcomes compared with transanal endorectal pull-through in Hirschsprung disease? A systematic review and meta-analysis.Pediatric surgery international · 2026Pooled it
- Long-term outcomes and quality of life of patients with Hirschsprung disease: a systematic review and meta-analysis.BMC gastroenterology · 2020Pooled it
- NETSArchives of disease in childhood · 2017Pooled it
- A systematic review of the quality of conduct and reporting of systematic reviews and meta-analyses in paediatric surgery.PloS one · 2017Pooled it
- Variability of outcome reporting in Hirschsprung's Disease and gastroschisis: a systematic review.Scientific reports · 2016Pooled it
- Trial
- Laparoscopic Versus Robotic Yancey-Soave Primary Pull-Through in Rectosigmoid Hirschsprung Disease: A Systematic Review of the Literature.Children (Basel, Switzerland) · 2026Review
- Safety and feasibility of one-stage neonatal approach for short-segment Hirschsprung's disease.PloS one · 2026Article
- Long-term outcomes of laparoscopic-assisted versus complete transanal endorectal pull-through technique for classic segment Hirschsprung's disease.Pediatric surgery international · 2024Article
- Evidence-based advances in minimally invasive surgery in infants with congenital gastrointestinal anomalies: a narrative review.Translational pediatrics · 2024Review
- Defining treatment success in children with surgical conditions.Archives of disease in childhood · 2024Article
- Postoperative rectal irrigation after laparoscopic Swenson pull-through: is early instrumentation safe?World journal of pediatric surgery · 2024Article
- Surgical management of short-segment Hirschsprung disease.World journal of pediatric surgery · 2024Review
- Controversies in Hirschsprung surgery.World journal of pediatric surgery · 2024Review
- Post-surgical Outcomes of Different Surgical Techniques in Hirschsprung's Disease: A Literature Review.Cureus · 2023Review
- Comparison between two minimally invasive techniques for Hirschsprung disease: transanal endorectal pull-through (TERPT) versus laparoscopic-TERPT.Pediatric surgery international · 2023Article
- A Novel Method for Identifying the Transition Zone in Long-Segment Hirschsprung Disease: Investigating the Muscle Unit to Ganglion Ratio.Biomolecules · 2022Article
- Comparison of clinical features and prognosis between ultrashort-segment and short-segment hirschsprung disease.Frontiers in pediatrics · 2022Article
- Quality of life outcomes in children after surgery for Hirschsprung disease and anorectal malformations: a systematic review and meta-analysis.World journal of pediatric surgery · 2022Review
- MYPT1 Down-regulation by Lipopolysaccharide-SIAH1/2 E3 Ligase-Ubiquitin-Proteasomal Degradation Contributes to Colonic Obstruction of Hirschsprung Disease.Cellular and molecular gastroenterology and hepatology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo compare outcomes following totally transanal endorectal pull-through (TTERPT) versus pull-through with any form of laparoscopic assistance (LAPT) for infants with uncomplicated Hirschsprung's disease.
designSystematic review and meta-analysis.
settingFive hospitals with a paediatric surgical service.
participants405 infants with uncomplicated Hirschsprung's disease.
interventionsTTERPT versus LAPT. PRIMARY AND SECONDARY OUTCOME MEASURES: PRIMARY OUTCOMES: mortality, postoperative enterocolitis, faecal incontinence, constipation, unplanned laparotomy or stoma formation, and injury to abdominal viscera. SECONDARY OUTCOMES: Haemorrhage requiring transfusion of blood products, abscess formation, intestinal obstruction, intestinal ischaemia, enteric fistula formation, urinary incontinence or retention, impotency and duration of procedure.
resultsFive eligible studies comprising 405 patients were identified from 2107 studies. All studies were retrospective case series, with variability in outcome assessment quality and length of follow-up. Operative duration was 50.29 min shorter with TTERPT (95% CI 39.83 to 60.74, p<0.00001). There were no significant differences identified between TTERPT and LAPT for incidence of postoperative enterocolitis (OR=0.78, 95% CI 0.44 to 1.38, p=0.39), faecal incontinence (OR=0.44, 95% CI 0.09 to 2.20, p=0.32) or constipation (OR=0.84, 95% CI 0.32 to 2.17, p=0.71).
conclusionsThis meta-analysis did not find any evidence to suggest a higher rate of enterocolitis, incontinence or constipation following TTERPT compared with LAPT. Further long-term comparative studies and multicentre data pooling are needed to determine whether a purely transanal approach offers any advantages over a laparoscopically assisted approach to rectosigmoid Hirschsprung's disease. TRIAL REGISTRATION NUMBER: PROSPERO registry- CRD42013005698.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.