ArticleZeitschrift fur Rheumatologie2015
[Lessons learnt from 15 years of investigator-initiated trials on axial spondyloarthritis].
Article in Zeitschrift fur Rheumatologie, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundClinical research is receiving an increasing amount of attention and is essential for improving treatment of patients with rheumatic diseases.
aimsThis article reports on 15 years of experience with conducting investigator-initiated studies on axial spondyloarthritis including ankylosing spondylitis.
resultsWe have organized and successfully conducted a series of open-labelled and placebo-controlled double-blind treatment studies and also non-interventional studies on this topic. The installation of a qualified and motivated trial unit and intensive collaboration with a statistician were crucial requirements for success. These results have increased our knowledge about the disease and changed and improved the diagnostic possibilities and the therapeutic options.
conclusionInvestigator-initiated trials are an important link between basic and clinical research and can substantially contribute to improvement of patient care. This kind of research should be more systematically funded in the future.
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25805515What OpenQuestion holds
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