Evidence map›Paper›PMID 25805456›Full record

Observational studyAmerican journal of surgery2015

An abdominal computed tomography may be safe in selected hypotensive trauma patients with positive Focused Assessment with Sonography in Trauma examination.

Mackenzie R Cook, John B Holcomb, Mohammad H Rahbar, Erin E Fox, Louis H Alarcon, Eileen M Bulger, Karen J Brasel, Martin A Schreiber, PROMMTT Study Group

Open access · greenAbstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in American journal of surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Imaging strategies for patients with multiple and/or severe injuries in the resuscitation room: a systematic review and clinical practice guideline update.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mackenzie R CookDepartment of Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mail Code L611, Portland, OR 97239, USA. Electronic address: cookmac@ohsu.edu.
John B HolcombDepartment of Surgery, University of Texas Health Science Center at Houston, Houston, TX, USA.
Mohammad H RahbarDepartment of Internal Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
Erin E FoxDepartment of Surgery, University of Texas Health Science Center at Houston, Houston, TX, USA.
Louis H AlarconDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Eileen M BulgerDepartment of Surgery, University of Washington, Seattle, WA, USA.
Karen J BraselDepartment of Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mail Code L611, Portland, OR 97239, USA.
Martin A SchreiberDepartment of Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mail Code L611, Portland, OR 97239, USA.
PROMMTT Study Group
The University of Texas Health Science Center at Houston · USOregon Health & Science University · USUniversity of Pittsburgh · USUniversity of Washington · US

Funding

U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9M
NCRR NIH HHS UL1 RR024148
6 · The paper itself

Abstract

backgroundPositive Focused Assessment with Sonography in Trauma examination and hypotension often indicate urgent surgery. An abdomen/pelvis computed tomography (apCT) may allow less invasive management but the delay may be associated with adverse outcomes.

methodsPatients in the Prospective Observational Multicenter Major Trauma Transfusion study with hypotension and a positive Focused Assessment with Sonography in Trauma (HF+) examination who underwent a CT (apCT+) were compared with those who did not.

resultsOf the 92 HF+ identified, 32 (35%) underwent apCT during initial evaluation and apCT was associated with decreased odds of an emergency operation (odds ratio .11, 95% confidence interval .001 to .116) and increased odds of angiographic intervention (odds ratio 14.3, 95% confidence interval 1.5 to 135). There was no significant difference in 30-day mortality or need for dialysis.

conclusionsAn apCT in HF+ patients is associated with reduced odds of emergency surgery, but not mortality. Select HF+ patients can safely undergo apCT to obtain clinically useful information.

Indexed as

Blood PressureMultiple TraumaRadiography, AbdominalAbdominal InjuriesAdultFemaleHumansHypotensionMaleMiddle AgedProspective StudiesReproducibility of ResultsTomography, X-Ray ComputedTrauma Severity IndicesUltrasonographyWounds, NonpenetratingComputed tomography scanFAST examinationTrauma

Identifiers

PMID25805456
PMCPMC4822493
OpenAlexW2158499779

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.