ArticleEuropean journal of applied physiology2015
Impact of handgrip exercise intensity on brachial artery flow-mediated dilation.
Article in European journal of applied physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Examination of Sex-Specific Participant Inclusion in Exercise Physiology Endothelial Function Research: A Systematic Review.Frontiers in sports and active living · 2022Pooled it
- The influence of vitamin C on the interaction between acute mental stress and endothelial function.European journal of applied physiology · 2017Trial
- The acute and chronic effects of local aerobic exercise on cardiovascular physiology.Experimental physiology · 2026Review
- Vascular function responses to resistance exercise followed by intermittent hypoxic exposure in untrained males.European journal of applied physiology · 2026Article
- Low-Load Blood Flow Restriction Training Enhances Brachial Blood Flow During Exercise but not Reactive Hyperemia in Experienced Climbers.Scandinavian journal of medicine & science in sports · 2026Article
- Acute Effects of Combining Weight and Elastic Resistance Exercise on Vascular Function in Older Adults.Geriatrics (Basel, Switzerland) · 2024Article
- Endothelial mechanobiology in atherosclerosis.Cardiovascular research · 2023Review
- Acute effect of high-intensity interval exercise on vascular endothelial function and possible mechanisms of wall shear stress in young obese males.Frontiers in physiology · 2022Article
- Brachial and carotid hemodynamic response to hot water immersion in men and women.American journal of physiology. Regulatory, integrative and comparative physiology · 2021Article
- Sex Differences in Exercise-Training-Related Functional and Morphological Adaptation of Rat Gracilis Muscle Arterioles.Frontiers in physiology · 2021Article
- Shearing the brain.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- Changes in circulating microRNA and arterial stiffness following high-intensity interval and moderate intensity continuous exercise.Physiological reports · 2020Article
- Effects of Catheterization on Artery Function and Health: When Should Patients Start Exercising Following Their Coronary Intervention?Sports medicine (Auckland, N.Z.) · 2019Review
- Effects of a Single Session of High- and Moderate-Intensity Resistance Exercise on Endothelial Function of Middle-Aged Sedentary Men.Frontiers in physiology · 2019Article
- Conduit Artery Diameter During Exercise Is Enhanced After Local, but Not Remote, Ischemic Preconditioning.Frontiers in physiology · 2018Article
- Vascular Adaptation to Exercise in Humans: Role of Hemodynamic Stimuli.Physiological reviews · 2017Review
- Effects of disturbed blood flow during exercise on endothelial function: a time course analysis.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2016Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePrevious studies that have examined the impact of exercise intensity on conduit artery endothelial function have involved large muscle group exercise which induces local and systemic effects. The aim of this study was to examine flow-mediated dilation (FMD) before and after incremental intensities of handgrip exercise (HE), to assess the role of local factors such as blood flow and shear rate on post-exercise brachial artery function.
methodsEleven healthy men attended the laboratory on three occasions. Subjects undertook 30 min of handgrip exercise at three intensities (5, 10 or 15 % MVC). Brachial artery FMD, shear and blood flow patterns were examined before, immediately after and 60 min post exercise.
resultsHandgrip exercise increased mean and antegrade shear rate (SR) and blood flow (BF) and reduced retrograde SR and BF (all P < 0.01). Exercise intensity was associated with a dose-dependent increase in both mean and antegrade BF and SR (interaction, P < 0.01). Post-hoc tests revealed that, whilst handgrip exercise did not immediately induce post-exercise changes, FMD was significantly higher 60 min post-exercise following the highest exercise intensity (5.9 ± 2.8-10.4 ± 5.8 %, P = 0.01).
conclusionsHandgrip exercise leads to intensity-and time-dependent changes in conduit artery function, possibly mediated by local increases in shear, with improvement in function evident at 1 h post-exercise when performed at a higher intensity.
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