Evidence map›Paper›PMID 25804726›Full record

ReviewMedizinische Klinik, Intensivmedizin und Notfallmedizin2016

[Catecholamines: pro and contra].

R Riessen, O Tschritter, U Janssens, M Haap

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. [65/m in cardiogenic shock : Preparation for the medical specialist examination: part 1].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026
    Article
  3. Review
  4. Multivalent stimulation of βNanoscale advances · 2022
    Article
  5. [Pharmacological therapy of circulatory shock].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2021
    Article
  6. [More negative than positive effects: adrenaline for cardiogenic shock].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2018
    Article
  7. Article
  8. [Levosimendan-no effect on multiorgan failure in septic shock].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

R RiessenInternistische Intensivstation, Department für Innere Medizin, Universitätsklinikum Tübingen, Otfried-Müller Str. 10, 72076, Tübingen, Deutschland. reimer.riessen@med.uni-tuebingen.de.
O TschritterInterdisziplinäre Notaufnahme, Marienhospital Stuttgart, Stuttgart, Deutschland.
U JanssensInnere Medizin, St.-Antonius-Hospital, Eschweiler, Deutschland.
M HaapInternistische Intensivstation, Department für Innere Medizin, Universitätsklinikum Tübingen, Otfried-Müller Str. 10, 72076, Tübingen, Deutschland.
Universitätsklinikum Tübingen · DEMarienhospital Stuttgart · DESankt-Antonius-Hospital Eschweiler · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatecholamines with vasopressor and inotropic effects are commonly used in intensive care medicine. The aim of this review is to explain some of the physiologic actions on which a catecholamine therapy is based, but also to elucidate the risks which are associated with an uncritical and excessive use of these drugs. SIDE EFFECTS: Emphasis is placed on the myocardial damage triggered by adrenergic overstimulation. There is considerable evidence that in conditions of severe heart failure, myocardial ischemia as well as cardiogenic and septic shock especially the use of catecholamines with predominant β-adrenergic effects (epinephrine, dobutamine, dopamine) can have a negative clinical impact. A simple cardiac risk marker might be a tachycardia. ADMINISTRATION: Vasopressor therapy with norepinephrine, based on individually applied perfusion parameters (e.g., urine output, lactate), however, seems justified in many conditions of shock and hemodynamic instability during deep analgosedation. In terms of a cardioprotective therapy, the administration of catecholamines, however, should always be reevaluated and titrated to the minimum deemed necessary.

Indexed as

Cardiotonic AgentsCatecholaminesContraindicationsCritical CareHemodynamicsHumansProcedural SedationRisk FactorsShockVasoconstrictor AgentsCardiotonic AgentsCatecholaminesVasoconstrictor AgentsBiogenic monoaminesCardiomyopathyIntensive care medicineSepsisShock

Identifiers

PMID25804726
OpenAlexW336382657

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.